Director, Clinical Pharmacology & MIDD — Cardio/Metabolic

GlaxoSmithKline plc; Greater London; On-site; GBP 150,000 - 250,000; Full time

Job summary

GSK is seeking a Director–level Clinical Pharmacologist to lead Model‑Informed Drug Development across the drug lifecycle, from first‑in‑human to lifecycle management. The role sits in CPMS R&I, reporting to RIIRU, with responsibility for strategy, evidence‑generation and regulatory readiness.

Applicants should have a PhD/MD/PharmD and 5+ years in clinical pharmacology, modelling/simulation and drug development, with experience in cardiovascular and metabolic diseases and cross‑functional

Qualifications

• PhD, MD, or PharmD required with 5+ years in clinical pharmacology and drug development.
• Experience in pharmacometrics and applying it to clinical questions.
• Experience designing Model-Informed Drug Development strategies.

Responsibilities

• Design and execute Model Informed and Clinical Pharmacology strategies.
• Develop and implement robust MIDD evidence strategies to de-risk RIIRU programs.
• Draft regulatory content and maintain knowledge of FDA/EMA/ICH expectations.
• Build cross-functional partnerships with CPQM, biology, data science and clinical teams.
• Provide scientific leadership and engage externally to influence regulatory dialogue.

Skills

Pharmacology

Pharmacometrics

Clinical pharmacology

Modeling & simulation

Education

PhD, MD, or PharmD

Job description

GSK is seeking a Director–level Clinical Pharmacologist to lead Model‑Informed Drug Development across the drug lifecycle, from first‑in‑human to lifecycle management. The role sits in CPMS R&I, reporting to RIIRU, with responsibility for strategy, evidence‑generation and regulatory readiness.

Applicants should have a PhD/MD/PharmD and 5+ years in clinical pharmacology, modelling/simulation and drug development, with experience in cardiovascular and metabolic diseases and cross‑functional