Director, Central Monitoring & Risk Analytics

Jazz Pharmaceuticals; Cambridge; On-site; GBP 90,000 - 130,000; Full time

Benefits offered by this job

Remote-friendly option

Job summary

Jazz Pharmaceuticals is seeking an Associate Director, Central Monitoring to lead the global central monitoring functions within Clinical Development Operations. You will define KRIs, build analytics, and translate insights into risk-based monitoring changes across trials.

Collaborate with Trial Risk Management, Site Monitoring, Data Management, and study teams to deploy monitoring resources effectively. Strong leadership and regulatory knowledge are essential.

Qualifications

• Typically, 8–10+ years of clinical research experience with central/statistical monitoring or RBQM.
• Proven ability to define, operationalize, and interpret KRIs and translate signals into monitoring decisions.
• Strong knowledge of ICH E6(R2/R3) and global regulatory requirements.

Responsibilities

• Lead and manage the Central Monitoring function and its staff.
• Define and maintain KRIs and centralized analytics at study/site/CRA level.
• Analyze data trends and determine monitoring strategy changes as needed.
• Own the process for triggering risk-based changes to monitoring plans.
• Support RBQM strategy documents and study monitoring plans.
• Lead central monitoring tech platforms and coordinate with IT and vendors.
• Present outputs and recommendations to study teams and senior leadership.
• Ensure documentation is inspection-ready and serve as SME during audits.

Skills

Central monitoring

RBQM

Data analytics

Stakeholder influence

People leadership

Communication

AI/ML in monitoring

Education

Bachelor's degree in life science or related

MS/MPH preferred

Tools

CTMS

EDC

Statistical analytics platforms

Job description

Jazz Pharmaceuticals is seeking an Associate Director, Central Monitoring to lead the global central monitoring functions within Clinical Development Operations. You will define KRIs, build analytics, and translate insights into risk-based monitoring changes across trials.

Collaborate with Trial Risk Management, Site Monitoring, Data Management, and study teams to deploy monitoring resources effectively. Strong leadership and regulatory knowledge are essential.