Lead Central Monitor — Global Risk & Data Integrity

Novartis UK; Greater London; Hybrid; GBP 54,000 - 100,000; Full time

Benefits offered by this job

Insurance plans

Retirement plans

Wellbeing resources

14 weeks paid parental leave

Job summary

Novartis UK is seeking a Lead Central Monitor to lead a team of Central Monitors and shape monitoring strategies across a global development portfolio. The role combines clinical oversight with data analytics to protect patient safety, trial quality, and data integrity in a hybrid setup based in Barcelona with European collaboration.

The ideal candidate has extensive pharmaceutical monitoring experience, leadership skills, and a strong understanding of GCP and risk-based quality management to

Qualifications

• University degree in Life Sciences, Business, Operations, or a related discipline.
• At least seven years of recent pharmaceutical or contract research organisation experience, including experience in clinical research.
• At least five years of experience in central or site monitoring, clinical data analytics, data management, or a related discipline.
• At least three years of recent people-management or team-leadership experience, with proven ability to develop high-performing teams.
• Strong understanding of clinical trial development, study execution, protocols, study risks, and clinical trial risk-management processes.
• Experience with centralised monitoring, Key Risk Indicators, Quality Tolerance Limits, and Risk-Based Quality Management approaches.
• Strong knowledge of Good Clinical Practice, International Council for Harmonisation standards, and relevant health-authority requirements.
• Strong analytical, digital, communication, and problem-solving skills, with the ability to interpret complex data and influence stakeholders in a global matrix environment.

Responsibilities

• Lead and develop a team of Central Monitors, building capability, engagement, and consistently high performance.
• Shape central and site monitoring strategies tailored to program, study, and Development Unit risks.
• Oversee trial-data surveillance, risk reviews, signal detection, and insight generation using Central Monitoring technology.
• Translate complex risk signals into actionable insights that enable Clinical Trial Teams to investigate and resolve issues.
• Partner with clinical, data, and risk-surveillance teams to implement effective monitoring and risk-mitigation approaches.
• Guide protocol development, risk assessment, and the design of study-specific Key Risk Indicators and thresholds.
• Ensure monitoring activities support clinical data integrity, regulatory compliance, audit readiness, and timely issue resolution.
• Drive continuous improvement through analytics, technology, innovation, lessons learned, and Risk-Based Quality Management.

Skills

People management

Leadership

Clinical trial knowledge

Analytical thinking

Cross-functional collaboration

Education

University degree in Life Sciences, Business, Operations, or related

Job description

Novartis UK is seeking a Lead Central Monitor to lead a team of Central Monitors and shape monitoring strategies across a global development portfolio. The role combines clinical oversight with data analytics to protect patient safety, trial quality, and data integrity in a hybrid setup based in Barcelona with European collaboration.

The ideal candidate has extensive pharmaceutical monitoring experience, leadership skills, and a strong understanding of GCP and risk-based quality management to