Clinical Trial Delivery Lead (Phase I–IV)

Discover International; Whilton; On-site; GBP 85,000 - 120,000; Full time

Job summary

Discover International is seeking a Clinical Trial Manager to lead the operational delivery of Phase I–IV trials for pharmaceutical and biotech sponsors in the UK, coordinating cross-functional teams from start-up through close-out.

You will own end-to-end trial management, oversee budgets and vendors, ensure ICH-GCP compliance, and mentor junior staff, with a focus on oncology, rare disease, or cardiovascular programs.

Qualifications

• Life sciences degree or equivalent experience.
• 4+ years in clinical trial management within a CRO/pharma/biotech setting.
• Proven line management/mentoring experience.
• Strong knowledge of ICH-GCP, UK/EU trial regulations, and risk-based monitoring.
• Experience managing study budgets and vendors.
• Experience in oncology, rare disease, or cardiovascular trials.

Responsibilities

• Own end-to-end trial management for assigned studies, ensuring delivery on time, on budget, and to quality standards.
• Line-manage CRAs/CRCs, overseeing site monitoring plans and performance.
• Serve as primary point of contact for sponsors, providing status updates and risk escalation.
• Develop and manage study budgets, timelines, and vendor/CRO oversight plans.
• Ensure inspection readiness and compliance with ICH-GCP, MHRA, and sponsor SOPs.
• Lead site selection, feasibility assessments, and study start-up activities.
• Chair internal and sponsor study team meetings.

Skills

Line management

ICH-GCP knowledge

Trial budget management

Vendor management

Risk-based monitoring

Experience in oncology/rare disease/cv

Education

Life sciences degree (or equivalent)

4+ years in clinical trial management (CRO/pharma/biotech)

Job description

Discover International is seeking a Clinical Trial Manager to lead the operational delivery of Phase I–IV trials for pharmaceutical and biotech sponsors in the UK, coordinating cross-functional teams from start-up through close-out.

You will own end-to-end trial management, oversee budgets and vendors, ensure ICH-GCP compliance, and mentor junior staff, with a focus on oncology, rare disease, or cardiovascular programs.