Clinical Data Manager

Warman O'Brien; United Kingdom; Remote; GBP 70,000 - 95,000; Full time

Job summary

Warman O'Brien is seeking a Clinical Data Manager for a fully remote role based in the UK. You will own data management deliverables, lead eCRF design and data cleaning, and mentor junior staff while coordinating with clients and QA during audits.

This position emphasizes strong leadership within a flexible, home-based environment, with responsibility for study-level planning and regulatory compliance across global projects.

Qualifications

• Bachelor's or Master's degree in health/pharmaceutical or related sciences.
• 3–5 years of pharmaceutical CDM experience.
• Deep understanding of ICH-GCP and data standards.
• Proven leadership in CDM activities.

Responsibilities

• Act as primary owner of data management deliverables, timelines, and status reports.
• Serve as first point of contact for technical or scope discussions during projects.
• Plan study resources and mentor junior staff; deliver training on EDC systems and data QC.
• Support audits and regulatory inspections with Study Binders and QA documentation.
• Lead study build and design, annotated CRFs, and UAT participation.
• Develop and maintain DMP, Data Management Project Plan, and DQRP.
• Oversee data review, query resolution, and SAE reconciliation, including vendor data streams.
• Manage post-go-live database changes, locks, and archival coordination.

Skills

Leadership

Data management

EDC systems

Regulatory compliance

Education

Bachelor's or Master's in life sciences

Tools

EDC platforms

UAT testing tools

Job description

Clinical Data Manager (100% Home-Based / Remote, UK)

Location: Remote (Home-based anywhere in the UK)

Employment Type: Full-time

Lead Data Management, Training & Client Relationships

• Project Ownership: Act as the primary day-to-day contact and ultimate owner of all data management deliverables, timelines, and status reports for assigned projects.
• Client & Scope Management: Serve as the first line of contact for technical, procedural, or out-of-scope discussions, participating in project kick-offs, investigator meetings, and bid defenses.
• Team Leadership & Training: Plan study-level resources (including timesheet reviews) and mentor junior staff. You will deliver training on EDC systems, dataflow, and QC processes to internal staff and clinical trial personnel.
• Compliance & Audits: Maintain clinical trial Data Management Study Binders and provide front-line support during client audits and regulatory inspections.

Perform Hands-on Data Management Activities

• Study Build & Design: Lead eCRF design, generate annotated CRFs, write Completion Instructions, and actively participate in database design and User Acceptance Testing (UAT).
• Data Strategy Documentation: Develop and maintain essential study documents, including the Data Management Plan (DMP), Data Management Project Plan, and Data Quality Review Plan (DQRP).
• Data Cleaning & Harmonisation: Oversee data review, query resolution, and Serious Adverse Event (SAE) reconciliation. You will manage complex non-CRF Third-Party Vendor data streams and resolve medical coding discrepancies.
• Lock & Archive: Flexibly manage post-go-live database modifications, execute soft/hard locks, and coordinate with QA for final archival documentation.

Qualifications and Experience

• Education: A Bachelor's or Master's degree in health/pharmaceutical sciences, physical/biological sciences, or chemistry fields.
• Experience: 3 - 5 years of experience in pharmaceutical clinical trial data management with a proven track record of meeting high-quality standards and driving customer satisfaction.
• Industry Knowledge: An in-depth understanding of clinical trial data management concepts, dataflows, relevant regulations (ICH-GCP), industry guidance, and data standards.
• Leadership Traits: Demonstrated strong leadership skills in CDM activities and a genuine desire to excel in leading complex data management projects.
• Say Goodbye to Assembly-Line Burnout: Escape the hyper-fragmented, siloed environment of giant conglomerates. Here, you will lead tight-knit project teams with true database ownership.
• Industry-Leading Stability: Our clients boasts an exceptionally high employee retention rate, offering an incredibly supportive, stable environment where your voice is heard.
• Uncompromised Quality: Join a company celebrated for operational pride, featuring a flawless track record of zero technical validation findings across hundreds of global health authority submissions (FDA, EMA, Health Canada).
• True Flexibility: Enjoy a mature, fully remote work-from-home infrastructure designed to support a healthy work-life balance.

Ready to make your next big career move?

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