Associate Director, Clinical Pharmacology & MIDD Strategy

Moderna Therapeutics Inc.; Harwell; Híbrido; GBP 90.000 - 130.000; Tempo integral

Benefícios oferecidos por esta vaga

Competitive healthcare

Fitness & mindfulness programs

Family building benefits

Generous paid time off

Resumo da vaga

Moderna is seeking a Clinical Pharmacology expert in Harwell to lead quantitative development strategies that integrate nonclinical and clinical data for dose selection and trial design. You will work across oncology, immunology, and rare diseases, leveraging PK/PD modeling and model-informed drug development.

You will collaborate with Pharmacometrics and QSP colleagues, support regulatory documentation, and contribute to Moderna’s mRNA platform advancements while embracing a 70/30 in-office

Qualificações

• PhD in Clinical Pharmacology or related field with minimum 5 years of industry experience in clinical pharmacology/DMPK/Pharmacometrics.
• Solid understanding of PK/PD modeling, exposure–response analysis, modeling and simulation.
• Experience integrating nonclinical and clinical evidence to support first-in-human predictions and regulatory decisions.

Responsabilidades

• Develop quantitative strategy plans for programs, including dose selection and optimization across development lifecycle.
• Perform and evaluate quantitative analyses, translating findings into recommendations.
• Collaborate with cross-functional teams to apply modeling to predict human PK/PD and inform trial design.

Conhecimentos

Quantitative pharmacology

PK/PD modeling

Exposure–response analysis

Model-informed drug development

Pharmacometrics

Clinical pharmacology

Data analysis

Regulatory science

Communication skills

Formação

PhD in Clinical Pharmacology or related field

Ferramentas

R

Phoenix WinNonlin

NONMEM

Monolix

Descrição da vaga

Moderna is seeking a Clinical Pharmacology expert in Harwell to lead quantitative development strategies that integrate nonclinical and clinical data for dose selection and trial design. You will work across oncology, immunology, and rare diseases, leveraging PK/PD modeling and model-informed drug development.

You will collaborate with Pharmacometrics and QSP colleagues, support regulatory documentation, and contribute to Moderna’s mRNA platform advancements while embracing a 70/30 in-office