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Antibody Discovery Scientist

CK Group

Slough

On-site

GBP 80,000 - 100,000

Full time

19 days ago

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Job summary

An innovative global biopharmaceutical company is seeking an Antibody Discovery Scientist to join their team in Slough. This exciting role involves utilizing state-of-the-art techniques in yeast display for the discovery and optimization of human antibodies. The successful candidate will design and perform selections using synthetic display libraries and prepare next-generation sequencing libraries for analysis. This position offers a unique opportunity to contribute to groundbreaking methodologies in antibody engineering while working in a collaborative environment focused on improving lives through advanced therapeutic solutions. If you are passionate about molecular biology and ready to make an impact, this role is for you.

Qualifications

  • PhD in molecular biology or protein biochemistry with antibody expertise.
  • Experience with in vitro display libraries for protein engineering.

Responsibilities

  • Discover and optimize human antibodies using cutting-edge yeast display.
  • Prepare and analyze NGS libraries to support antibody engineering.

Skills

Molecular Biology
Protein Biochemistry
In Vitro Display Libraries
Biochemical Techniques
Computational Platforms

Education

PhD in relevant field

Tools

Next Generation Sequencing (NGS)
Flow Cytometry
Surface Plasmon Resonance
Bio-layer Interferometry

Job description

CK Group are recruiting for an Antibody Discovery Scientist, to join a global pharmaceutical company, based in Slough, on a contract basis, initially for 12 months.

Salary:
PAYE GBP28.53 per hour or UMB GBP38.80 per hour.

Antibody Discovery Scientist Role:

  • Using cutting-edge yeast display for the discovery and optimisation of human antibodies aligned with therapeutic targets.
  • Design, construct, and perform selections using bespoke synthetic display libraries to support in antibody discovery and optimisation projects.
  • The preparation of next generation sequencing (NGS) libraries and their analyses to support antibody discovery and engineering of lead molecules.
  • Contribute to the development and implementation of new methodologies in antibody display and engineering.
  • Present experimental data at cross-functional meetings.

Your Background:
  • A PhD (or equivalent) with molecular biology and protein biochemistry knowledge ideally within the antibody space.
  • Knowledge and experience in the use of in vitro display libraries for either discovery, affinity maturation, or other protein engineering.
  • Skills in information technology and other computational platforms such as molecular visualisation and next generation sequencing data analysis would be advantageous.
  • Demonstrable experience of biochemical techniques for the characterisation of macromolecules such as flow-cytometry, surface plasmon resonance or Bio-layer interferometry.

Company:
Our client is a global biopharmaceutical company focused on creating value for people living with severe diseases in immunology and neurology now and into the future.

Location:
This role is based at our client’s site in Slough.

Apply:
It is essential that applicants hold entitlement to work in the UK. Please quote job reference in all correspondence.

Please note:
This role may be subject to a satisfactory basic Disclosure and Barring Service (DBS) check.
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