Applications Scientist

Schrödinger, LLC; United Kingdom; Remote; GBP 50,000 - 90,000; Full time

Job summary

Join a forward-thinking company dedicated to improving human health through advanced computational methods. As an Applications Scientist, you will leverage your expertise in computational chemistry and structural biology to support customers in the use of innovative software for drug discovery. This role offers the opportunity to engage in cutting-edge research, collaborate with talented teams, and contribute to the development of groundbreaking solutions in molecular modeling. Enjoy a flexible working environment, competitive salary, and a range of employee benefits that support your professional and personal growth.

Benefits

Employee Equity Plan

Volunteer Programs

Donation Match

Counseling Services

Travel Insurance

Flexible Working Environment

Generous Time Off

Qualifications

• PhD in computational chemistry or related field with expertise in RNA/DNA modeling.
• Experience in molecular dynamics simulations and ligand-based drug design.

Responsibilities

• Provide scientific support and guidance to customers using our life science software.
• Engage in cutting-edge research and publish findings in scientific papers.

Skills

Computational Chemistry

Bioinformatics

Structural Biology

Molecular Dynamics Simulations

Ligand-based Drug Design

Programming (Python)

Machine Learning Methods

Excellent English Communication

Education

PhD in Computational Chemistry

Postdoctoral Research Experience

Tools

SHAPE-MaP

DMS-MaPseq

SPR

ITC

EMSA

FRET

Cryo-EM

SAXS

Job description

Schrödinger seeks an Applications Scientist to join us in our mission to improve human health and quality of life through the development, distribution, and application of advanced computational methods!

Schrödinger is on the cutting edge of computer-aided drug discovery and materials science where our software suites continue to transform the design of therapeutics and materials. FEP+, WaterMap, Glide, BioLuminate, and LiveDesign are just a few examples of the applications we’ve created. As a member of our European Applications Science team, you’ll train and guide customers in their use of our groundbreaking molecular modelling suites, provide strategic scientific support, and address challenging problems in drug discovery. In this role, you’ll help advance Schrödinger’s modeling capabilities for RNA and DNA as therapeutic targets or modalities.

We’re seeking to fill this position in one of our offices in Germany (Mannheim, Munich) or remotely in the UK (Greater London or the South East).

Who will love this job:

• A computer-aided molecular design enthusiast (both in theory and application) - specifically, someone with solid experience in structure-based drug design
• An excellent communicator and presenter with superb organisational skills
• A dedicated scientist who’s willing to learn and deliver results
• A creative collaborator who enjoys helping others solve problems
• A self-motivated team player who takes ownership of projects and manages their own time well

What you’ll do:

• Provide scientific support to current and prospective customers, including demonstrating optimal use of our life science software suites, facilitating interactions between customers and product development teams, and offering scientific guidance
• Engage in cutting-edge methodological scientific research and advise our customers on best practices for computational modelling
• Publish scientific papers and present at conferences

What you should have:

• PhD in computational chemistry, bioinformatics, structural biology, or a related field
• Deep scientific expertise in the modeling of nucleic acids (RNA/DNA) as therapeutic modalities or targets
• Experience in one or more of the following: molecular dynamics simulations/enhanced sampling/free energy calculation methods, ligand-based drug design, quantum mechanics, structural modeling
• A solid understanding of the commercial drug discovery process
• Excellent English language skills (both verbal and written)
• Willingness to travel
• Additional qualifications such as:
• Postdoctoral research and/or relevant experience in the commercial sector
• Expertise in applying machine learning methods to drug discovery
• Programming experience (preferably Python)
• Experience with experimental techniques relevant to RNA/DNA-targeted drug discovery such as SHAPE-MaP, DMS-MaPseq, SPR, ITC, EMSA, FRET, cryo-EM, SAXS, and in vitro transcription/translation assays

As a Schrödinger employee, you'll enjoy our employee equity plan, volunteer programs, donation match, counseling services, and travel insurance. We offer a competitive salary, flexible working environment, and generous time off.

As an equal opportunity employer, Schrödinger hires outstanding individuals into every position. We value engagement, teamwork, and passion for our mission. We are committed to creating a safe, inclusive environment that respects diversity in all its forms, recognizing that diversity fosters innovation and creativity.