Antibody Discovery Scientist

TieTalent; Slough; On-site; GBP 80,000 - 100,000; Full time

Job summary

An innovative global biopharmaceutical company is seeking an Antibody Discovery Scientist to join their team in Slough. This role offers the opportunity to work on cutting-edge projects involving the discovery and optimization of human antibodies using advanced yeast display technology. The successful candidate will be responsible for designing bespoke synthetic display libraries and analyzing next-generation sequencing data to support antibody engineering. This is an exciting opportunity to contribute to groundbreaking methodologies in the field and present findings at cross-functional meetings. Join a team dedicated to improving the lives of patients with severe diseases in immunology and neurology.

Qualifications

• PhD or equivalent in molecular biology with knowledge in antibody research.
• Experience with in vitro display libraries for protein engineering.

Responsibilities

• Discover and optimize human antibodies using yeast display technology.
• Prepare and analyze NGS libraries for antibody engineering.

Skills

Molecular Biology

Protein Biochemistry

Biochemical Techniques

Flow Cytometry

Data Analysis

Education

PhD in Molecular Biology

Tools

Next Generation Sequencing (NGS)

Computational Platforms

Job description

CK Group - Science, Clinical and Technical

CK Group is recruiting for an Antibody Discovery Scientist to join a global pharmaceutical company based in Slough, on a contract basis initially for 12 months.

Salary: PAYE £28.53 per hour or UMB £38.80 per hour.

Antibody Discovery Scientist Role:

1. Using cutting-edge yeast display for the discovery and optimisation of human antibodies aligned with therapeutic targets.
2. Design, construct, and perform selections using bespoke synthetic display libraries to support antibody discovery and optimisation projects.
3. Prepare next generation sequencing (NGS) libraries and analyze data to support antibody discovery and engineering of lead molecules.
4. Contribute to the development and implementation of new methodologies in antibody display and engineering.
5. Present experimental data at cross-functional meetings.

Your Background:

• A PhD (or equivalent) with molecular biology and protein biochemistry knowledge, ideally within the antibody space.
• Knowledge and experience in the use of in vitro display libraries for discovery, affinity maturation, or other protein engineering.
• Skills in information technology and computational platforms such as molecular visualization and NGS data analysis would be advantageous.
• Demonstrable experience with biochemical techniques for characterizing macromolecules, such as flow cytometry, surface plasmon resonance, or Bio-layer interferometry.

Company:

Our client is a global biopharmaceutical company focused on creating value for people living with severe diseases in immunology and neurology.

Location:

This role is based at the client's site in Slough.

Apply:

Applicants must hold entitlement to work in the UK. Please quote the job reference (Apply online only) in all correspondence.

Note: This role may be subject to a satisfactory basic Disclosure and Barring Service (DBS) check.