Senior Scientist Bioreactor Process Design (all genders)

Sandoz France; Toulouse; Sur place; EUR 90 000 - 120 000; Plein temps

Résumé du poste

Sandoz is seeking a Senior Scientist Bioreactor Process Design in Toulouse, France, to lead development and tech transfer of upstream perfusion and intensified fed-batch processes for biotherapeutics.

You will design, execute, and analyze DOE studies, mentor staff, and act as a subject matter expert for cGMP and process design, collaborating with clients and partners to drive successful technology transfer.

Qualifications

• Master’s in engineering, Biochemistry, Biology, or related field with 8+ years experience or Ph.D. with 6+ years experience.
• Proficiency in English (verbal and written).
• Expert in bioreactor cell culture and perfusion technology development and CMC filings.

Responsabilités

• Drive development and tech transfer of upstream perfusion/intensified fed-batch processes for biotherapeutics.
• Prepare and run bench-scale bioreactors and related equipment.
• Lead Process Characterization projects and serve as SME for cell culture and bioreactor processes.
• Communicate experimental plans and results to teams and clients clearly.

Connaissances

Bioreactor development

DOE

Statistical analysis

Cell culture

Perfusion tech

Scientific communication

Formation

Master’s in engineering

PhD in Engineering/Biochemistry/Biology (optional)

Outils

JMP

R

Python

Ambr systems

Description du poste

We’re excited to share this opportunity is part of the Sandoz acquisition of Just-Evotec Biologics in Toulouse. Through this opportunity you will impact the lives of hundreds of millions of people through bold ideas supported by an inclusive, agile company culture. Join us to help make healthcare fairer and faster, help us to pioneer access to medicine!

Location: Toulouse, France.

Type of contract: Permanent

We’re looking for a passionate and curious Senior Scientist Bioreactor Process Design to join our team.

If you’re excited by new challenges, solving complex problems, and learning every step of the way, you might just be the perfect fit.

In this role, you’ll have the opportunity to drive impactful projects, collaborate with bright minds, and explore uncharted territories.

You’ll have the freedom to ask the hard questions, think outside the box, and find creative solutions that push us forward. It’s a role where your curiosity will fuel both your personal growth and the success of the team.

What You’ll Do

• Driving development and tech transfer of early and late-stage (characterization and validation) upstream perfusion/intensified fed-batch processes for biotherapeutics manufacturing as well as technology development projects.
• Prepare and run bench-scale bioreactors and bioreactor-related equipment (controllers, pumps, autoclaves, etc.).
• This may include but not limited to, build and autoclave bioreactor parts and assemblies as well as assisting with bench-scale bioreactor operations (daily sampling and analytics, inoculation activities, run preparation, and troubleshooting).
• Serve as a functional area lead for Biosimilar early and late-stage Process Characterization (PC) projects as well as technology development projects.
• Serve as an internal technical resource for cGMP manufacturing and Process Design, as well as a resource and subject matter expert for external clients and partners for cell culture and bioreactor processes (small scale models, process transfer, and scale up).
• Communicate experimental plans and data to teams and clients clearly and effectively, including communicating scientific information to a diverse set of audiences, including external clients, vendors, and technology development collaborators.
• Independently design, execute, and analyze statistically designed experiments (DOE).
• Author SOPs, reports, and slides which summarize, organize, and interpret experiment results with review by appropriate team members.
• Train and mentor junior staff and interns within a matrix reporting structure
• Potential for weekend work and being on-call for critical bioreactor runs.

Who You Are

• Master’s in engineering, Biochemistry, Biology, or related field with 8+ years of experience or Ph.D. in Engineering, Biochemistry, Biology, or related field with 6+ years of experience.
• Proficiency in both verbal and written English is essential.
• Expert in bioreactor cell culture and perfusion technology development and tech as well as CMC sections authoring regulatory filings.
• Experience in Biosimilar development.
• Experience with commercial process development, process characterization, and validation.
• Expertise in design of experiments (DOE) and statistical analysis.
• Experience with high throughput cell culture (e.g. HT assays, robotics such as Ambr systems, lab automation, or multi-omic data) is a plus.

Pluses

• Experience analyzing data in tools such as JMP, R, or Python.
• General understanding of cell biology, fluid dynamics, and biotransport as well as knowledge in other functional areas (downstream purification and analytical sciences).
• General understanding of circuits (grounding, power, signal, etc.).
• Experience working in a cGMP or clean room setting (this job is non-GMP but knowledge of GMP is helpful for process/tech transfer activities).

Why Sandoz?

Generic and Biosimilar medicines are the backbone of the global medicines industry. Sandoz, a leader in this sector, provided more than 900 million patient treatments across 100+ countries in 2024 and while we are proud of this achievement, we have an ambition to do more! With investments in new development capabilities, state-of-the‑art production sites, new acquisitions, and partnerships, we have the opportunity to shape the future of Sandoz and help more patients gain access to low‑cost, high-quality medicines, sustainably. Our momentum and entrepreneurial spirit is powered by an open, collaborative culture driven by our talented and ambitious colleagues, who, in return for applying their skills experience an agile and collegiate environment with impactful, flexible‑hybrid careers, where diversity is welcomed and where personal growth is encouraged!

The future is ours to shape!

ENG : In the frame of our Diversity policy, Evotec considers, with equal competences, all applications including people with disabilities.