Senior Process Engineer - USP (H / F) – Lyon, France

Verley; Lyon; Sur place; EUR 50 000 - 70 000; Plein temps

Résumé du poste

A biotechnology company in Lyon seeks a Senior Process Engineer USP to lead development and optimization of microbial fermentation processes. Candidates should have 5-8 years of experience in USP development and strong analytical skills. The role involves close collaboration with internal teams and external partners to ensure successful tech transfer to manufacturing. Join us in revolutionizing food production!

Prestations

Employee stock option plan

Innovative work environment

Entrepreneurial culture

Qualifications

• 5–8 years of experience in USP development and scale-up within the biotech, food, or biopharma industry.
• Proven expertise in fermentation process development and scale-up strategies.
• Strong analytical and problem-solving skills.

Responsabilités

• Lead USP development activities from laboratory scale through to commercial manufacturing.
• Prepare detailed USP documentation and provide technical input during tech transfer.
• Work closely with cross-functional teams to ensure full process integration.

Connaissances

USP development

Microbial fermentation

Process optimization

Analytical skills

Team collaboration

Description du poste

About us

Verley is a biotechnology company based in Lyon, focused on developing dairy proteins through precision fermentation. Our aim is to offer sustainable, high-quality alternatives to traditional animal-based ingredients, contributing to the evolution of food production methods. We bring together a team of scientists and engineers with complementary expertise, working to turn promising technologies into concrete applications for the food industry.

Position overview

As Verley scales up its proprietary processes from laboratory to full-scale commercial production, we are reinforcing our upstream processing (USP) expertise. The Senior Process Engineer USP will act as a subject matter expert (SME) for microbial fermentation, ensuring the robustness and scalability of our production processes. Reporting to the Lead Process Engineer, this role bridges R&D and industrialization, supporting the development, optimization, and transfer of fermentation processes to our external manufacturing partners.

This position requires strong technical expertise in USP, hands-on involvement in process development and troubleshooting, and the ability to collaborate closely with internal R&D teams as well as external CMOs.

Key Responsibilities

Process Development & Scale-Up

• Lead USP development activities from laboratory scale through to commercial manufacturing (strain inoculation, seed train, fed-batch / continuous fermentation strategies).
• Optimize productivity, yield, and process robustness in coordination with R&D teams.
• Define and validate critical process parameters; contribute to process characterization and validation studies.
• Analyze fermentation data and implement technical improvements across scales.

Tech Transfer & CMO Support

• Prepare detailed USP documentation (process descriptions, protocols, batch records).
• Provide technical input during tech transfer to CMOs, ensuring smooth scale-up to commercial production.
• Participate in on-site troubleshooting and support manufacturing campaigns as needed.
• Review and validate CMO process data and documentation.

Cross-functional Collaboration

• Work closely with downstream, analytical, and quality teams to ensure full process integration.
• Support regulatory and quality documentation related to USP processes.
• Contribute to risk assessments and process control strategies.

Technical Leadership

• Act as the internal USP subject matter expert, ensuring knowledge transfer within the team.
• Provide guidance to junior engineers and technicians in USP operations.
• Promote best practices, technical rigor, and continuous improvement across USP activities.

Profile

• 5–8 years of experience in USP development and scale-up within the biotech, food, or biopharma industry.
• Proven expertise in fermentation process development (microbial systems, fed-batch / continuous, scale-up strategies).
• Demonstrated experience in scaling USP processes from lab to commercial manufacturing scale.
• Familiarity with tech transfer and external manufacturing collaboration (CMOs / CDMOs).
• Strong analytical and problem-solving skills, hands-on mindset.
• Fluent in English; French is a plus.
• Willingness to travel occasionally to support industrial partners.

What we offer

• An innovative environment, where scientific excellence and curiosity drive cutting-edge developments in food science.
• An entrepreneurial culture, where each team member has the opportunity to make a real difference and directly contribute to the company’s growth.
• A global mindset, with a diverse team of experts from around the world, combining unique perspectives to tackle complex challenges.
• A shared commitment, where we all share in Verley’s success and growth through our employee stock option plan (BSPCE).

At Verley, we celebrate diversity and inclusivity and are proud to welcome applicants of all backgrounds in our mission to revolutionize the future of food and biotechnology.