Postdoctoral Researcher: RNA Networks & Evolution

CNRS - National Center for Scientific Research; France; On-site; EUR 30,000 - 45,000; Full time

Job summary

CNRS invites applications for a First Stage Researcher (R1) to join the Synthetic Biosystems team within the Structural Biology of the Cell Laboratory (BIOC, UMR 7654) at CNRS – École polytechnique, in France. The project studies RNA reaction networks combining autocatalysis, reproduction and variation to explore Darwinian-like properties.

You will design and test RNA networks, perform biochemical measurements, analyse dynamics and contribute to meetings, reports and publications.

Qualifications

• Knowledge of RNA biochemistry and molecular biology.
• Experience with reaction networks and autocatalysis.
• Familiarity with fluorescence microscopy and image analysis.
• Ability to design experiments, record data and write scientific reports.

Responsibilities

• Design, produce and purify functional RNAs and reaction-network components.
• Characterise autocatalytic and self-reproducing RNA systems with biochemical measurements.
• Investigate ligation, recombination and information-transfer in RNA networks.
• Analyse effects of compartmentalisation and environmental cycles on network dynamics.
• Document results and contribute to reports, publications and presentations.
• Participate in team discussions, collaborations, and project activities.

Skills

RNA biochemistry

Molecular biology

Reaction networks

Autocatalysis

Fluorescence microscopy

Image analysis

Quantitative data processing

Scientific writing in English

Laboratory notebook keeping

Experimental design

Nucleic acid purification

Tools

Microscopy

Biophysical instrumentation

Job description

CNRS invites applications for a First Stage Researcher (R1) to join the Synthetic Biosystems team within the Structural Biology of the Cell Laboratory (BIOC, UMR 7654) at CNRS – École polytechnique, in France. The project studies RNA reaction networks combining autocatalysis, reproduction and variation to explore Darwinian-like properties.

You will design and test RNA networks, perform biochemical measurements, analyse dynamics and contribute to meetings, reports and publications.