Postdoctoral Researcher (M/F) in High-Resolution Human Retinal Imaging

CNRS - National Center for Scientific Research; France; On-site; EUR 40,000 - 60,000; Full time

Job summary

CNRS – Institut Langevin in Paris invites applications for a postdoctoral researcher to contribute to the development of a novel technology for functional imaging of the human retina at cellular resolution. You will work within the SCALE-ORG project to push toward a prototype suitable for clinical imaging validation.

The role involves experimental optics, interferometry and data analysis, with an emphasis on robust imaging under eye movements and translational biomedical applications.

Qualifications

• PhD in physics, optics, photonics or related field.
• Strong experience in experimental optics or optical imaging.
• Experience with interferometry, OCT, microscopy or coherent imaging.
• Experience in data analysis and scientific programming (Python, MATLAB).
• Ability to design, conduct and analyze experiments independently.
• Interest in biomedical imaging and translational optical instrumentation.
• Good communication and teamwork in a multidisciplinary setting.

Responsibilities

• Development, optimization, and characterization of an FFOCT imaging system for human optoretinography.
• Improvement of robustness of image acquisition and functional measurements, particularly eye movements and interferometric fluctuations.
• Development and validation of algorithms for extracting functional photoreceptor responses.
• Development of quantitative methods for extracting reproducible biomarkers.
• Contribution to the integration of hardware and software developments into a prototype for future clinical validation.
• Analysis of experimental results and contribution to dissemination and publication.

Skills

Experimental optics

Optical imaging

Interferometry

OCT imaging

Python

MATLAB

Independent researcher

Biomedical imaging

Education

PhD in physics/optics/photonic

Tools

Python

MATLAB

Job description

Organisation/Company CNRS Department Institut Langevin Research Field Engineering Physics Technology Researcher Profile First Stage Researcher (R1) Application Deadline 23 Nov 2026 - 23:59 (UTC) Country France Type of Contract Temporary Job Status Full-time Hours Per Week 35 Offer Starting Date 1 Jan 2027 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

As part of the SCALE-ORG project, supported by the PSL Valorisation pre-maturation program, we are seeking a postdoctoral researcher to contribute to the development of a novel technology for functional imaging of the human retina at cellular resolution.

The project is based on optoretinography (ORG) using full-field optical coherence tomography (FFOCT), which enables non-invasive measurements of photoreceptor responses to light stimulation.

The objective is to advance this approach toward a prototype compatible with clinical imaging requirements, capable of providing robust and reproducible functional measurements, particularly for future applications in the investigation of age-related macular degeneration (AMD).

The successful candidate will contribute to the experimental and methodological developments of the project, including:

• Development, optimization, and characterization of an FFOCT imaging system for human optoretinography.
• Improvement of the robustness of image acquisition and functional measurements, particularly with respect to eye movements and interferometric fluctuations.
• Development and validation of algorithms for extracting functional photoreceptor responses.
• Development of quantitative methods for extracting reproducible biomarkers.
• Contribution to the integration of hardware and software developments into a prototype intended for future clinical validation.
• Analysis of experimental results and contribution to their scientific dissemination and publication.

The project will be carried out at Institut Langevin (CNRS, ESPCI Paris – PSL), in Paris, within a research team developing innovative optical imaging methods for high-resolution, in vivo imaging of the human retina.

SCALE-ORG is part of a technology transfer initiative aimed at bridging the gap between cellular-resolution functional imaging techniques and clinical applications in ophthalmology.

The research will build on existing experimental imaging systems and methodological developments, as well as the team's established clinical collaborations.

Candidates must hold a PhD in physics, optics, photonics, biomedical engineering, or a closely related field.

The desired qualifications and skills include:

• Strong experience in experimental optics and/or optical imaging.
• Knowledge of interferometry, OCT, microscopy, or coherent imaging techniques.
• Experience in data analysis and scientific programming (Python, MATLAB, or equivalent).
• Ability to design, conduct, and analyze experiments independently.
• Interest in biomedical imaging and the development of optical instrumentation for translational applications.
• Good scientific communication skills and the ability to work effectively in a multidisciplinary team.

Previous experience in retinal imaging, adaptive optics, or interferometric signal processing would be an advantage.