Postdoctoral/IR Position in Genomics (M/F)

TN France; Paris; Sur place; EUR 40 000 - 70 000; Plein temps

Résumé du poste

An established player in cancer research is seeking motivated postdoctoral fellows for an exciting opportunity in Paris. The role focuses on studying DNA replication dynamics and genome stability using advanced genomic techniques. This innovative position offers a chance to contribute to groundbreaking research, bridging basic science and clinical applications. Ideal candidates will possess a PhD in biology or bioinformatics and have strong computational skills. Join a collaborative team dedicated to advancing cancer research and improving patient outcomes in a supportive environment.

Prestations

Collective catering

Transportation reimbursement (up to 70%)

Supplementary health insurance

Qualifications

• PhD in biology or bioinformatics required.
• Strong computational and statistical skills essential.

Responsabilités

• Join the 'Replication Program and Genome Instability' team.
• Utilize genomic techniques to study DNA replication dynamics.

Connaissances

Computational skills

Statistical skills

Molecular biology

Cellular biology

Single-cell omics

Imaging techniques

Neurogenesis

English proficiency

Formation

PhD in biology

PhD in bioinformatics

Description du poste

Postdoctoral/IR Position in Genomics (M/F), Paris

Client:

Institut Curie

Location:

Paris, France

Job Category:

Other

EU work permit required:

Yes

Job Reference:

a1e851be676e

Job Views:

2

Posted:

29.04.2025

Expiry Date:

13.06.2025

Job Description:

Institut Curie Research Center is a major player in cancer research and treatment. It comprises a hospital group and a research center with over 1000 employees, aiming to advance basic research and translate knowledge into improved diagnosis, prognosis, and therapies for cancer, bridging basic research and innovation for patient benefit.

Laboratory

We seek motivated postdoctoral fellows to join our "Replication Program and Genome Instability" team at Institut Curie, Paris. The team utilizes advanced high-throughput genomic techniques and data analysis to study DNA replication dynamics and genome stability in normal and cancer cells at both population and single-cell levels.

The Project

DNA replication is essential for cell division, involving the activation of thousands of origins to duplicate the human genome. Its regulation is crucial during development and differentiation, with misregulation linked to diseases like cancer. Our project aims to develop innovative single-molecule/cell methodologies combining imaging, sequencing, modeling, and bioinformatics to study replication in mammalian cells and model organisms, elucidating its role in genome instability and disease.

References

1. Promonet A., et al. Nat. Commun. 11:3940 (2020)
2. Wang, W. et al. Mol. Cell, 81, (2021)
3. Gnan, S., et al. Nat. Commun., 13, 2329 (2022)
4. Emerson, Nature. 606:812–819 (2022)
5. Li J., et al. Cell, (2023)
6. Liu Y., et al. Nucleic Acids. Res., gkac1239 (2023)

Constraints and Risks

• Short travel periods
• Use of biological/chemical agents
• Potential work with mouse models

Required Skills and Qualifications

• PhD in biology, bioinformatics, or related field (or in progress)
• Strong computational/statistical skills or solid molecular/cellular biology background
• Interest in genome biology
• Experience with single-cell omics, imaging, neurogenesis, or related areas is a plus
• Proficiency in English and good communication skills

Desired Abilities

• Independence and teamwork skills
• Motivated, curious, and enthusiastic

Benefits

Collective catering, transportation reimbursement (up to 70%), supplementary health insurance

Position Location

Paris, 5th arrondissement

Application Instructions

Please submit your CV, motivation letter, and three references. All opportunities are accessible to individuals with disabilities. Note: Non-passport holders may require a work permit. For more information, visit our Blog. Do not include bank details in your application. Applications must be submitted via the 'Apply now' button.