Job offer

European Commission; France; Sur place; EUR 30 000 - 45 000; Plein temps

Résumé du poste

A leading research lab at the Jussieu campus of Sorbonne University in Paris is seeking a postdoctoral researcher to investigate NMDA receptor regulation through electrophysiological recordings and behavioral analysis. The role requires expertise in brain slice techniques and experience with rodents. Successful candidates will collaborate in a dynamic team, contributing to groundbreaking research in a stimulating environment overlooking the Seine.

Qualifications

• Experience in performing electrophysiological recordings in acute brain slices.
• Experience in in vivo recordings is a plus.
• Completed certified training for proper work with rodents.

Responsabilités

• Perform electrophysiological recordings in hippocampal area CA2 and CA1.
• Conduct basic behavioral testing and histological imaging.
• Communicate results in weekly meetings and data clubs.

Connaissances

Electrophysiological recordings

Data analysis

Behavioral testing

Histological imaging

Formation

PhD degree in Neuroscience or related field

Description du poste

Organisation/Company CNRS Department Neuro-SU Research Field Neurosciences Biological sciences Researcher Profile Recognised Researcher (R2) Country France Application Deadline 1 Aug 2025 - 00:00 (UTC) Type of Contract Temporary Job Status Full-time Hours Per Week 35 Offer Starting Date 1 Aug 2025 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

Postdoctoral researcher expected to perform electrophysiological recordings in hippocampal area CA2 and CA1 in vivo and/or in acute hippocampal slices. This is a position funded by the ANR AetaSocCog, which will investigate a novel mechanism underlying NMDA receptor regulation. These experiments will also require some basic behavioral testing as well as fundamental histological imaging.

The candidate will record synaptic and cellular activity in vivo and in acute hippocampal slices from hippocampal area CA2. Experiments will be discussed and results presented in weekly meetings with the team, and in data clubs with the Neuroscience department.

The lab is located in the center of Paris, at the Jussieu campus of Sorbonne University. The windows of our lab overlook the Seine river. The project of this research will be to examine hippocampal area CA2, and specifically, to examine how the environment and experience alters the physiological properties of the neurons in this region in both healthy and diseased contexts. Specifically, we will examine how NMDA receptors are modulated by the extracellular Aeta fragment. Specifically, how this fragment contributes to CA2 NMDA receptor plasticity in healthy and diseased mouse models. We are a small team consisting of one PhD, one postdoc, one technician, one assistant engineer and Rebecca Piskorowski and several interns. This position is funded by the the Agence National Recherche project AetaSocCog.

Optimally, candidates will have experience performing electrophysiological recordings in acute brain slices. Top-ranking candidates will also have had experience perfoming in vivo recordings. Applicants are expected to perform all analysis, experimental planning and figure preparation and data organization. It is desirable for candidates to have experience working with mice and have completed European certified training for proper work with rodents in a laboratory. Candidates will be expected to communicate in written and spoken English with fellow lab members.