Post-doctoral position in biological chemistry

Bordeaux Neurocampus; Bordeaux; Sur place; EUR 42 000 - 54 000; Plein temps

Résumé du poste

Bordeaux Neurocampus invites applications for a Post-doctoral position in biological chemistry focusing on synthesis and imaging of non-natural sugars. The project aims to develop molecular tools to modulate ECM rigidity in neuronal tissue and study impacts on plasticity.

Candidate will develop labelling strategies for fluorescence microscopy and validate findings across cellular models, working with PMCI and IINS groups under senior researchers Frédéric Friscourt and Morgane Rosendale.

Qualifications

• Organic synthesis (glycan chemistry).
• Cell labelling and imaging techniques as part of the project.

Responsabilités

• Develop molecular tools and cell labelling strategies from organic sugar synthesis to fluorescence imaging.
• Validate tools in different cellular models.

Connaissances

Organic synthesis

Description du poste

Post-doctoral position in biological chemistry

As part of the Interdisciplinary and Exploratory Research project (RIE) "GlycoMechano - Crosslinking of glycans to modulate the mechanical properties of the brain", we are recruiting a Post-Doctoral fellow whose work will focus on biological chemistry for the synthesis and imaging of non-natural sugars.

The aim of the project is to develop molecular tools capable of modulating the rigidity of the extracellular matrix (ECM) of a neuronal tissue in order to study the effect of a rigidification of the synaptic environment on plasticity.

Your mission will be to develop molecular tools and the cell labelling strategy from organic sugar synthesis to their visualisation by fluorescence microscopy at various levels of resolution, including their validation in different cellular models.

You will be working within two laboratories: the Molecular Photonics, Chemobiology and Imaging (PMCI) group and the Interdisciplinary Institute for Neuroscience (IINS) under the joint supervision of Frédéric Friscourt (Chemobiology) and Morgane Rosendale (Neuroscience).

Skills we are looking for:

• Organic synthesis (mostly glycan chemistry)

Publication: 29/01/26
Last update 29/01/26