Post-doctoral fellow (f / m) on ID23-2 in the Structure of Biology group

ESRF; Grenoble; Sur place; EUR 34 000 - 45 000; Plein temps

Résumé du poste

L'ESRF recherche un chercheur postdoctoral passionné pour rejoindre son groupe de biologie structurale à Grenoble. Le candidat retenu appliquera des techniques avancées de cristallographie pour résoudre des problèmes complexes en biologie, tout en collaborant avec des experts internationaux. Ce poste offre également l'occasion de développer un programme de recherche indépendant tout en soutenant les utilisateurs externes.

Prestations

Environnement de travail innovant et international

Collaboration avec des experts mondiaux

Soutien à la qualité de vie

Compensation compétitive et allocations

Aide financière pour déménagement à Grenoble

Qualifications

• Diplôme de doctorat obtenu il y a moins de 3 ans.
• Connaissance de l'analyse cristallographique macromoléculaire.
• Anglais courant exigé en tant que langue de travail.

Responsabilités

• Appliquer des techniques d'apprentissage machine aux expérimentations.
• Participer aux programmes de recherche internes.
• Contribuer à l'opération de la ligne de rayonnement.

Connaissances

Biologie structurale

Production de protéines

Analyse cristallographique X

Interaction avec le personnel multidisciplinaire

Python

Formation

PhD en biophysique, biologie ou science connexe

Description du poste

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Post-doctoral fellow (f/m) on ID23-2 in the Structure of Biology group, Grenoble

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Client:

ESRF

Location:

Grenoble, France

Job Category:

Other

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EU work permit required:

Yes

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Job Reference:

c7b168bf2379

Job Views:

3

Posted:

30.06.2025

Expiry Date:

14.08.2025

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Job Description:

Serial Synchrotron Crystallography is now a standard tool for structural biology at ESRF. It has applications at both room temperature and cryogenic temperatures with and without time resolution. Although significant progress has been made in experimental design, sample delivery, data collection strategies, and data analysis, challenges remain. One such challenge is the de-segregation of mixed populations of structural data. The origin of this diversity could be due to phenomena such as radiation damage, (de)hydration, and incomplete penetration of ligands or light.

This postdoctoral position will focus on applying previously developed machine learning techniques to single image serial experiments. The candidate will apply and refine these approaches on in-house data as well as data collected by external research groups at ESRF. As a postdoctoral researcher in the Structural Biology Group, responsibilities include participating in in-house research programs, contributing to beamline operation, and supporting external users as a local contact. There will also be opportunities to develop an independent research program.

Expected profile

• PhD in biophysics, biology, or a closely related science obtained less than 3 years ago
• A strong background in structural biology and protein production is desirable
• Knowledge of macromolecular X-ray crystallographic analysis
• Ability to interact with multidisciplinary staff and facility users
• Proficiency in English (working language at ESRF)
• Basic scripting/Python knowledge

Working conditions

The salary will be based on relevant qualifications and professional experience.

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What we offer:

• Join an innovative international research institute with a diverse workforce from 38 countries
• Collaborate with global experts to advance science and societal challenges
• Live in a vibrant city in the Alps, Europe's Green Capital 2022
• Enjoy a workplace supporting your quality of life
• Benefit from a competitive compensation and allowances package, including financial support for relocation to Grenoble