Post-Doc Scientist Antibody Discovery & Engineering

Sanofi Group; França; Híbrido; EUR 32 000 - 52 000; Tempo integral

Resumo da oferta

Sanofi Group in France seeks a highly motivated Post-Doctoral Researcher to join our Large Molecule Research platform. The role focuses on discovering and engineering 2-in-1 antibodies for innovative therapeutics, requiring autonomy and collaboration across multiple methodologies.

The candidate will develop state-of-the-art display-based discovery methods, engineer bispecific formats, and characterize candidates biochemically and biophysically, contributing to pipeline integration and potential

Qualificações

• PhD in Protein Engineering or related field required.
• Industrial experience is a plus.
• Demonstrated expertise in antibody discovery and/or engineering.
• Hands-on experience with phage display and/or yeast display.
• Strong data analysis and interpretation skills.
• Excellent written and oral communication in English.

Responsabilidades

• Develop and implement state-of-the-art methods for antibody discovery using display technologies (phage or yeast).
• Engineer and optimize 2-in-1 bispecific antibody formats for therapeutic applications.
• Perform biochemical and biophysical characterization of antibody candidates.
• Establish robust methodologies ready to be deployed in the discovery pipeline.
• Conduct high-throughput screening and analyze large datasets with strong analytical rigor.
• Collaborate with cross-functional teams and present findings internally.
• Contribute to publications and/or patent filings when applicable.
• Ensure seamless integration of new methods into the existing pipeline.

Conhecimentos

Antibody discovery

Bispecific engineering

Data analysis

Biochemistry

Display technologies

Cross-functional teamwork

English fluency

Formação académica

PhD in Protein Engineering or related field

Descrição da oferta de emprego

About the RoleWe are looking for a highly motivated and talented Post-Doctoral Researcher to join our team in the Large Molecule Research platform at Sanofi. This position offers a unique opportunity to work on an ambitious and cutting-edge project focused on the discovery and engineering of 2-in-1 antibodies for the development of innovative therapeutic antibodies.This is a complex and challenging project that will require strong scientific autonomy, versatility across multiple methodologies, and excellent collaborative skills in a cross-functional environment.Key Responsibilities* Developing and implementing state-of-the-art technological methods for innovative antibody discovery using display technologies (phage display and/or yeast display)* Engineer and optimize 2-in-1 bispecific antibody formats for therapeutic applications* Perform biochemical and biophysical characterization of antibody candidates* Establishing robust and transferable methodologies, ready to be deployed in support of therapeutic areas* Conduct high-throughput screening and analyze large datasets with strong analytical rigor* Work in close collaboration with cross-functional teams* Present findings internally and contribute to publications and/or patent filings* Ensuring seamless integration of these new methods into the existing discovery pipelineRequired Profile* PhD in Protein Engineering or a related field* Industrial experience would be an asset* Demonstrated expertise in antibody discovery and/or engineering* Strong hands-on experience with display technologies (phage display and/or yeast display)* Solid knowledge of screening methodologies and biochemistry techniques* Bilingual: digitally fluent, and experimental mindset* Strong data analysis skills and ability to draw meaningful scientific conclusions* Ability to work autonomously while being a strong team player* Experience in cross-functional collaboration is a plus* Excellent written and oral communication skills in EnglishWhat We Offer* A stimulating scientific environment within a world-leading biopharmaceutical company* Access to state-of-the-art technologies and platforms* Opportunities to contribute to innovative therapeutic programsA collaborative and inclusive team culture