PhD Thesis - Study of the Link Between Obesity and Peritoneal Metastatic Potential in Ovarian a[...]

Karlstad University; Strasbourg; Sur place; EUR 60 000 - 80 000; Plein temps

Résumé du poste

Eine innovative Forschungseinrichtung sucht einen Doktoranden, um die Verbindung zwischen Fettleibigkeit und peritonealen Metastasen bei Krebs zu untersuchen. In einem dynamischen Umfeld werden Sie an der Schnittstelle von Krebsbiologie und Pharmakologie arbeiten, indem Sie modernste Bildgebungstechniken und bioanalytische Methoden nutzen. Diese Position bietet die Möglichkeit, in einem multidisziplinären Team zu arbeiten und Ihre Fähigkeiten in der wissenschaftlichen Forschung zu erweitern. Wenn Sie eine Leidenschaft für Onkologie und die Motivation haben, neue Fähigkeiten zu erlernen, könnte dies die perfekte Gelegenheit für Sie sein.

Qualifications

• Starke Kenntnisse in Krebsbiologie oder Entzündungstherapie sind von Vorteil.
• Erfahrung in der wissenschaftlichen Forschung und Tierexperimenten ist wünschenswert.

Responsabilités

• Durchführung von In-vitro- und In-vivo-Studien zur Untersuchung von Metastasen.
• Überwachung immunologischer und entzündlicher Parameter.

Connaissances

Cancer biology

Inflammation pharmacology

Molecular biology techniques

Biochemical analysis

Flow cytometry

Histological analyses

Analytical skills

Communication skills in English

Formation

Master Degree or equivalent

Outils

Cell culture

Non-invasive imaging

Description du poste

PhD Thesis - Study of the Link Between Obesity and Peritoneal Metastatic Potential in Ovarian and Breast Cancer Murine Models

The Université catholique de Louvain (UCLouvain) is internationally recognized for research and teaching quality in many different fields of expertise. The Louvain Drug Research Institute (LDRI) - UCLouvain invites applications for a PhD position to investigate the relationship between obesity and peritoneal metastatic potential in ovarian and breast cancer using murine models. This research will be conducted within two leading laboratories: the REMA lab, specializing in cancer imaging, and the BPBL lab, focusing on bioanalysis and the pharmacology of bioactive lipids. Obesity is increasingly recognized as a critical factor influencing cancer progression and metastasis. This PhD project will explore the role of obesity-induced inflammation in promoting peritoneal metastases in ovarian and breast cancer models. The research will integrate advanced imaging techniques, bioanalytical methods, and pharmacological analyses to better understand the molecular and cellular mechanisms underlying these interactions.

The candidate will be involved in:

• In vitro (cell culture, transwell assays, …) and in vivo studies in mice (animal monitoring, body weight, blood sampling, in vivo tumor growth assays, non-invasive imaging)
• Monitoring of immune and inflammatory parameters (Molecular biology techniques, biochemical analysis, flow cytometry, histological analyses…)

Research Field: Pharmacological sciences » Other

Education Level: Master Degree or equivalent

Skills/Qualifications

• A strong background in cancer biology or inflammation pharmacology is an advantage.
• Previous experience in scientific research (internships, research projects, or laboratory work): Experience/training in animal experimentation, molecular biology and biochemical analysis is an advantage.
• Strong analytical skills and a willingness to engage with experimental animal models (FELASA certificate for animal handling is a plus, if not, the candidate will have to obtain this certificate through training at the very beginning of the thesis).
• Excellent communication skills in English (written and spoken).

Specific Requirements

• Interest in oncology/cancer biology, inflammation pharmacology, or metabolic disorders.
• Ability to work independently and collaboratively within multidisciplinary teams.
• Motivation for scientific research and willingness to learn new skills and techniques.

Languages: ENGLISH

Work Location(s)

Number of offers available: 1