Job offer

European Commission; France; Sur place; EUR 40 000 - 60 000; Plein temps

Résumé du poste

Une institution de recherche renommée propose un contrat de doctorat de 3 ans axé sur les dynamiques et la morphologie mitochondrial dans le cadre des maladies cardiaques. Le candidat collaborera avec des experts et participera à des projets de recherches innovants. Une maîtrise des techniques biochimiques et une expertise en expérimentation animale sont requises, tout en offrant un cadre de travail stimulant au sein d'une équipe dynamique.

Qualifications

• Expérience en gestion de lignées murines transgéniques.
• Maîtrise des méthodes biochimiques pour l'analyse mitochondriale.
• Bonne maîtrise de l'anglais.

Responsabilités

• Génotyping, collecte de tissus, biochimie mitochondriale.
• Mesures physiologiques cardiaques et analyse structurale des mitochondries.
• Réalisation d'analyses métabolomiques.

Connaissances

Expérimentation animale

Techniques biochimiques

Analyse biophysique

Anglais (B2-C1)

Formation

Diplôme en expérimentation animale

Description du poste

Organisation/Company: CNRS
Department: Institut de Biochimie et Génétique Cellulaires
Research Field: Chemistry, Biochemistry, Physics, Biophysics, Biological sciences, Biological engineering
Researcher Profile: First Stage Researcher (R1)
Country: France
Application Deadline: 26 Jun 2025 - 23:59 (UTC)
Type of Contract: Temporary
Job Status: Full-time
Hours Per Week: 35
Offer Starting Date: 1 Oct 2025
Is the job funded through the EU Research Framework Programme? No
Is the Job related to staff position within a Research Infrastructure? No

Offer Description

The 3-year PhD contract is part of an ANR 'DynaMitoPatho' co-financing and 'MetabOptic' regional project in collaboration with Dr. Pierre Bon's laboratory (XLILM Research Center, Limoges). Recruitment will take place within the BioDynaMit laboratory located at IBGC-UMR5095.

The laboratory has a high level of expertise in cellular and mitochondrial energy metabolism, with equipment and animal models for studying mitochondrial metabolism in metabolic maintenance and cardiac pathophysiology.

The recruited person will work under Dr. Philippe Pasdois, an expert in cardiac energetics and mitochondrial function, in collaboration with Dr. Arnaud Mourier, an expert in mitochondrial genetic diseases and transgenic models.

The PhD project will focus on the role of mitochondrial dynamics and morphology in genome maintenance and cardiac disease. The candidate should have experience in managing transgenic murine lines and biochemical methods for mitochondrial analysis, including isolation, respiration assays, electrophoresis, spectroscopy, and microscopy.

The activities include genotyping, tissue collection, mitochondrial biochemistry, metabolomics, cardiac physiological measurements, and structural analysis of mitochondria.

Desired skills include a diploma in animal experimentation, proficiency in biochemical techniques, and good command of English (B2-C1 level).

Research Field: Biological sciences, Biological engineering
Years of Research Experience: None