Opérateur de saisie - Assurances H / F

Tessi; Châtillon; Sur place; EUR 30 000 - 50 000; Plein temps

Résumé du poste

An established research institution is seeking a dedicated engineer to join their Molecular Mechanism of Chromosome Dynamics group. In this pivotal role, you will explore the causes of chromosomal aberrations in cancer, employing cutting-edge techniques such as CRISPR/Cas9 and advanced microscopy. Collaborating closely with a dynamic team, you'll contribute to groundbreaking research aimed at improving cancer diagnostics and therapies. This opportunity offers a full-time fixed-term contract with the potential for renewal, allowing you to make a significant impact in the fight against cancer while working in a supportive and inclusive environment.

Prestations

Collective Catering

Transportation Fee Reimbursement

Supplementary Health Insurance

Qualifications

• Expertise in microscopy and molecular biology is highly recommended.
• Candidates should have experience with tissue culture models.

Responsabilités

• Conduct cell culture and genome editing using CRISPR/Cas9 technology.
• Implement digital droplet PCR and develop imaging techniques.

Connaissances

Microscopy

Molecular Biology

CRISPR/Cas9

Data Analysis

Cell Culture

Formation

Engineering Degree

Master's Degree in Biology

Outils

Digital Droplet PCR

Lentivirus Approaches

Super Resolution Microscopy

Description du poste

Créer une alerte emploi pour cette recherche

Dernière mise à jour: il y a 2 jours

• Offre sponsorisée

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Description de poste

Institut Curie is a major player in the research and fight against cancer. It consists of a Hospital group and a Research Center of more than 1000 employees with a strong international representativeness. The objective of the Research Center is to develop basic research and to use the knowledge produced to improve the diagnosis, prognosis, and therapeutics of cancers as part of the continuum between basic research and innovation serving the patient.

Laboratory

The engineer will work in the Molecular Mechanism of Chromosome Dynamics group headed by Daniele Fachinetti ().

The project

The selected candidate will study the causes and consequences of centromere aberrations in cancer using interdisciplinary approaches in cell and cancer cell models. The selected candidate will work together with members of the Fachinetti group to elucidate the repair mechanisms acting at broken centromeres. One of the tasks will be to develop novel imaging approaches to detect chromosome translocations.

Activity description

• Cell culture, clone isolation and characterization, treatment with various compounds;
• Genome editing with CRISPR / Cas9 technology and lentivirus approaches;
• Microscopy techniques (live cell imaging, super resolution, multicolor FISH for karyotype analysis);
• Implementation of the digital droplet PCR for measuring repetitive elements;
• Development of expansion microscopy on metaphase chromosomes;
• Molecular biology assays (DNA, RNA and protein extraction-Implementing, cloning);
• Data analysis;
• Communication of results at meetings.

Training and Skills required

Candidates must hold an engineering degree or a master's degree in biology. Previous expertise in microscopy, in the usage of tissue culture models and molecular biology are recommended. Professional English level is required.

All our opportunities are open to people with disabilities

Contract information

Type of contract : Fixed-term contract.

Starting date : From July / September.

Duration : 18 months renewable

Working time : full time

Remuneration : according to the current grids

Benefits : Collective catering, reimbursement of transportation fees up to 70%, supplementary health insurance

Location of the position : Paris 5th (downtown)

Reference : NA

Research funds are available thanks to a Research Center program at I. Curie and public generosity.

Contact

To apply, please send your CV and cover letter (2 pages maximum)

Deadline for application : 31st of August

Institut Curie is an inclusive, equal opportunity employer

and is dedicated to the highest standards of research integrity.