Medical Physicist - Radiation Dosimetry

Medpace; Lyon; On-site; EUR 70,000 - 110,000; Full time

Benefits offered by this job

Competitive compensation

Health, retirement, and PTO benefits

Occasional WFH after training

Office-based culture

Job summary

Medpace Imaging Core Laboratory seeks a full-time, office-based Medical Physicist to lead quantitative image reconstruction and dosimetry for clinical trials involving radio-theranostic agents. You will advise on protocols, design imaging measures, and perform QA across PET/CT, SPECT/CT, and planar imaging, ensuring regulatory compliance.

The role requires a PhD or MSc in physics with strong dosimetry experience, proficiency in MIRD S-values and OLINDA/EXM, and prior exposure to clinical trials

Qualifications

• PhD in physics or related field with at least 2 years' dosimetry experience.
• Or MSc in physics with at least 5 years' dosimetry experience.
• Expertise in quantitative image reconstruction for nuclear medicine.
• Experience with MIRD S-values, 3D-RD and/or OLINDA/EXM 1.0 software.
• Experience with gamma, PET/CT, SPECT/CT dosimetry is preferred.

Responsibilities

• Advise on radiation dosimetry and nuclear imaging for clinical trial protocols.
• Design imaging and dosimetry measures for diagnostic or therapeutic radionuclides.
• Perform QA checks on nuclear imaging and dosimetry data per protocol requirements.
• Calibrate scanners using phantom scans and dosimetry conversion factors.
• Conduct image reconstruction and analysis (PET/CT, SPECT/CT, planar imaging).
• Compute dosimetry (%ID/g, biological half-life, TIAC, dose) in tissues using software.
• Ensure compliance with MIRC and ICRP radiation safety guidelines.
• Prepare project status reports and timelines for imaging components.
• Work in compliance with GCP, 21 CFR Part 11, SOPs, and trial protocols.

Skills

Quantitative image reconstruction

Nuclear medicine imaging

Quality assurance

Dosimetry calculations

Image analysis

Education

PhD in physics or related field with dosimetry experience

MSc in physics with dosimetry experience

Tools

MIRD S-values

3D-RD

OLINDA/EXM 1.0

Job description

Expertise in quantitative image reconstruction (nuclear medicine images)

Our imaging services are growing rapidly, and we are currently seeking a full-time, office-based Medical Physicist to join our team. If you want an exciting career where you will use your previous education and expertise to develop and grow your career even further, then this is the opportunity for you. You will work as part the Medpace Imaging Core Laboratory team leading clinical trials radio-theranostic agents.

Responsibilities

• Advice and review relating to radiation dosimetry and nuclear imaging on clinical trial protocols proposed by sponsors
• Design of imaging and dosimetry measures for use with diagnostic or therapeutic radionuclides
• Perform quality assurance checks on nuclear imaging and dosimetry data to ensure protocol specific requirements are met
• Scanner calibration by the analysis of phantom scans and calculation of the dosimetry conversion factor
• Image reconstruction and analysis (PET/CT, SPECT/CT and/or planar nuclear imaging)
• Dosimetry calculation (%ID/g, biological half-life, TIAC, estimated dose) in normal organ and tumor tissues using off the shelf and proprietary software
• Ensure compliance with MIRC and ICRP guidelines for radiation safety protection
• Compile and maintain project-specific status reports and project timelines associated with imaging components of clinical trials
• Perform project specific tasks in compliance with Good Clinical Practices (GCP), regulatory requirements (21CFR Part 11), applicable departmental and companywide SOPs, and project specific protocols.

Qualifications

• PhD degree in physics or in other relevant field with at least 2 years’ experience in dosimetry calculation for internal radiotherapy (targeted radio nucleotide therapy)
• Or Master degree in physics or in other relevant field with at least 5 years’ experience in dosimetry calculation for internal radiotherapy (targeted radio nucleotide therapy)
• Expertise in quantitative image reconstruction (nuclear medicine images)
• Expertise in internal radiotherapy and dosimetry calculation using MIRD S-values, 3D-RD and/or OLINDA/EXM 1.0 software
• Experience with internal radiation dosimetry for gamma, positron and alpha emitting radionuclides would be favored
• Experience working with clinical trials or within the pharmaceutical environment is preferred.

Medpace Overview

Medpace is a full-service clinical contract research organization (CRO) providing phase l-lV clinical development services to the biotechnology, pharmaceutical, and medical device industries. Our mission is to accelerate the global development of safe and effective medical therapeutics through the advancement of clinical research. We leverage in-country regulatory and therapeutic expertise across all major therapeutic areas including oncology, cardiology, metabolic, endocrinology, central nervous system, and anti-viral and anti-infective. Headquartered in Cincinnati, Ohio, we employ more than 6,500 people across 40+ countries.

Why Medpace?

When you join Medpace, you become part of an innovative team that brings cutting-edge therapies to market while building a meaningful and rewarding career focused on scientific excellence and improving patient outcomes around the world through continuous learning and cross-functional collaboration.

Purpose-Driven Work

• Work alongside physicians, scientists, and industry-leading experts committed to advancing the global development of medical therapeutics through clinical research excellence

Collaborative Culture

• Contribute to an interactive team environment that empowers decision making, creative thinking, and continuous learning through open communication and mutual trust.
• Leadership throughout Medpace is both accessible and approachable

Continuous Growth & Development

• Office based environment with on-site mentors
• Defined career paths with clear advancement opportunities
• Industry renowned onboarding and training programs designed to accelerate professional development
• Ongoing training and continuous learning opportunities throughout your career
• An environment that encourages employees to influence change, contribute ideas, and grow quickly

Other Employee Benefits

• Competitive compensation programs that recognize and reward performance
• Comprehensive health, wellness, retirement, and PTO benefits
• Office based culture with occasional WFH that provides flexibility for eligible positions after training
• Company-sponsored social events

Please note benefits may vary based on country.

What To Expect Next

A Medpace team member will review your application and if your profile matches our current needs, you will be contacted for an interview. While we review all applications carefully, we are unable to respond to every applicant, and only candidates selected for interviews will be contacted.