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Une entreprise innovante recherche un stagiaire Master2 pour une mission en modélisation physique dans le traitement focal du cancer de la prostate. Le stage, d'une durée de 6 mois, inclut le développement de modèles mathématiques pour divers traitements, en collaboration avec des experts médicaux. Le candidat idéal est autonome et motivé, avec une formation en informatique, mathématiques appliquées, physique ou ingénierie biomédicale.
Référence : FocalProstate
Fonction : Ingénierie et technique / Recherche / Développement
Secteur d'activité : Santé / Social / Paramédical
Localisation : Brest (29)
Type de contrat : Stage / Temps plein
Durée : 4 à 6 mois
Date de début : 05/03/2025
Niveau : Bac+4/5 (M)
Indemnités : moins de 1600 € / mois
LaTIM - INSERM
Groupe : Univ Brest
In the past, we developed a planning system for low-dose focal brachytherapy for prostate cancer. To explore other treatment modalities such as cryotherapy, microwave therapy, and electroporation, mathematical models that define the treated area based on physical parameters (tissue type, energy, treatment time, etc.) need to be created. These models are crucial for estimating precise treatment criteria, such as tumor coverage and impact on organs at risk. These criteria are then used to define a cost function that, along with an objective function, enables the optimization algorithm to converge toward a clinically acceptable solution. For this, we use the simulated annealing method for its non-convex and multiparametric search capabilities, which help avoid local minima.
The goal of the internship will be to create mathematical and algorithmic models for different treatments using real data and literature. These models must be precise and efficient, and they will be tested in our planning software. For each treatment modality, the cost function, with optimized criteria estimates in terms of computation time and complexity, must also be developed. The aim is to ensure rapid convergence suitable for a clinical context. The treatment plan results will be presented and evaluated by a urologist experienced in these treatments.
Master2 in computer science, applied mathematics, physics, biomedical engineering. Autonomy, open-mindedness, and motivation.
The trainee will join the INSERM UMR1101 Laboratory of Medical Information Processing (LaTIM, Brest, France, https://latim.univ-brest.fr). We will work in collaboration with different academic, hospital, and company partners within a national project.
6-month internship with compensation according to the legal amount in France.