Job offer

European Commission; France; Sur place; EUR 35 000 - 55 000; Plein temps

Résumé du poste

Une institution de recherche en France propose un poste de Junior Professeur pour intégrer l'intelligence artificielle dans la biologie structurale. Ce rôle vise à former les étudiants et à renforcer les collaborations internationales, contribuant à des défis sociétaux majeurs en biologie et santé.

Qualifications

• Aucune expérience de recherche requise.
• Ouvert à tous, sans restrictions d'âge ou de nationalité.

Responsabilités

• Développer des approches novatrices en biologie structurale et biomédicale à l'aide de l'IA.
• Former des étudiants en Master et Doctorat dans le cadre de programmes internationaux.

Formation

Titulaire d'un doctorat ou diplôme équivalent

Description du poste

Biological sciences » Biological engineering

Organisation/Company CNRS Department Direction des ressources humaines Research Field Chemistry » Biochemistry Physics » Biophysics Biological sciences » Biological engineering Researcher Profile First Stage Researcher (R1) Country France Application Deadline 14 Jul 2025 - 23:59 (UTC) Type of Contract Other Job Status Full-time Hours Per Week 35 Offer Starting Date 23 Jun 2025 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

The emergence of digital approaches and artificial intelligence technologies, in which CNRS is actively involved, is considerably accelerating scientific discoveries. It represents a major driver of progress, particularly in the field of structural biology, enabling the search for new molecular configurations, the atomic-level understanding of biological mechanisms, and the development of therapeutic, diagnostic or biotechnological strategies.
In this context, the Junior Professorship aims both to implement AI approaches for the development of integrative structural biology and to strengthen one of our leading laboratories in the field, the AFMB, which is highly connected to both the national and international scientific communities.
This Junior Professorship is part of two of the six major societal challenges, along with artificial intelligence and health and the environment, by conducting research at the interface of biological and digital sciences.

The AFMB unit in Marseille is a leading research center in structural biology, renowned for its expertise in X-ray crystallography, cryo-electron microscopy and multidisciplinary approaches (biochemistry, biophysics). It benefits from a solid network, notably within FRISBI (French Infrastructure for Integrated Structural Biology), and cutting-edge technologies for medical and environmental applications (pathophysiological mechanisms, therapies, biotechnologies). The Chair aims to integrate artificial intelligence to elucidate the structure-function relationships of macromolecules, predict structures from protein sequences and design new therapeutic and biotechnological tools. This project, combining experimentation and digital technology, will strengthen the training of Master's and PhD students and contribute to the thematic priorities on living matter.

The Junior Professorship project lies at the interface of structural biology, bioinformatics and artificial intelligence (AI), applied to life and health sciences. It aims to develop innovative approaches using AI to design synthetic proteins capable of mimicking or creating enzymatic reactions, and interacting with protein partners, modulating their pathophysiological modes of action. These proteins will also be used to screen organic molecules, in silico, in vitro or in cristallo. The project is in line with the virology and glycobiology themes, taking advantage of the laboratory's equipment and expertise and its platforms (PBSIM, CAZy, MaSC). It includes challenges ranging from the design of new proteins to the validation of their functionalities, integrating interdisciplinary collaborations.

The project will be integrated into the CIVIS European University, the Master's program in Structural Biology and Bioinformatics, as well as the doctoral training courses of the France 2030 TIGER initiative. It is structured around two main pillars: 1) AI in Computational Biology – Students will gain foundational knowledge in artificial intelligence and its applications in protein structure prediction and de novo protein design, with practical uses in structure interpretation, complex modeling, and drug development. 2) AI Applications in Biology and Biomedicine – This component will explore AI advancements beyond protein folding, with a particular focus on AI-driven drug discovery and virtual screening.
The overarching goal is to equip students with the skills and understanding necessary to engage with emerging AI-driven opportunities in life sciences and to support their professional development in this rapidly evolving field.
The program will integrate the site's international policy via A*MIDEX, the Plinus Cursus doctoral program, Erasmus+, and will benefit from the AFMB laboratory's networks as well as support from the H2020 program.

The CNRS is developing a strong policy in favor of open science. Open science consists of making research results "as accessible as possible and closed as necessary". As such, the CNRS aims to make 100% of the texts of publications resulting from the work of its laboratories accessible , in particular through deposit in HAL. The data produced must also be made available and reusable, except for specific restrictions. In addition, the guiding principles of individual evaluation have been revised in accordance with the DORA declaration, to be more qualitative and to take into account all facets of the researcher's profession.

The dissemination of the results will be done through world-class scientific productions: publications, patents, software... In addition, the results will be communicated to various targets such as scientific communities, media, decision makers, general public, schools, etc., with an adapted calendar. Specific tools may be developed such as websites, newsletters, meetings, international symposia, summer schools and conferences.

The relationship between science and society is now recognized as a full dimension of scientific activity. The project will develop this dimension in synergy with all the partners. The resulting research work will contribute to informing public decision-making. Participatory science initiatives may be initiated with actors from the project's socio-economic and cultural eco-system.

Research Field Biological sciences » Biological engineering Years of Research Experience None

Additional Information

Eligibility criteria

holders of a doctorate or a PhD or equivalent degree or applicants who have gained scientific. There is no restriction on the age or nationality of applicants. All CNRS positions are accessible to people with disabilities, with special arrangements for tests made necessary by the nature of the disability.