Laboratory Operations Manager

JR France; Paris; Sur place; EUR 40 000 - 60 000; Plein temps

Résumé du poste

Le laboratoire Wyart à l'Institut du Cerveau de Paris recherche un Responsable de laboratoire expérimenté. Innovant et dynamique, vous serez chargé de gérer les opérations quotidiennes et de coordonner des projets scientifiques complexes en biologie moléculaire. Vous travaillerez avec une équipe interdisciplinaire pour soutenir la recherche sur les populations neuronales et leurs implications sur la santé et la maladie.

Qualifications

• Expertise en biologie moléculaire nécessaire pour la gestion des projets scientifiques.
• Compétence en CRISPR/Cas pour la génération de lignées transgéniques.
• Expérience en HCR multiplexé et transcriptomique à cellule unique.

Responsabilités

• Gérer les stocks et l'organisation des réactifs de biologie moléculaire.
• Coordonner l'intégration des nouveaux membres et leur formation.
• Représenter le laboratoire lors des réunions de l'institut.

Connaissances

Discipline

Autonomie

Proactivité

Supportivité

Dynamisme

Rigueur

Compétences didactiques

Description du poste

The Paris Brain Institute (ICM) is an international research centre that brings patients, researchers, and medical doctors together to understand and treat disorders of the nervous system. Training of young researchers with diverse origins, backgrounds, and training is essential.

The Wyart lab at the Paris Brain Institute is a highly interdisciplinary team composed of molecular and cell biologists, physiologists, physicists, computer scientists, and ecologists. To facilitate collaboration, the Wyart lab is recruiting a lab manager.

MISSIONS AND ACTIVITIES OF THE LAB MANAGER

The lab seeks an experienced manager to contribute to the organizational and operational aspects of the research activities. The candidate will work under the supervision of Claire Wyart, the lab head, and project managers Feng Quan and Kevin Fidelin. The role involves molecular biology expertise to advance understanding of movement-related neuronal populations in the brainstem, at molecular, circuit, and behavioral levels, in health and disease, across vertebrate models. The position requires high discipline, versatility, autonomy, proactivity, supportiveness, didactic skills, and dynamism to teach good practices to lab members. Rigor and organizational skills are essential. The main responsibilities include:

Qualifications for scientific projects

• CRISPR/Cas-based generation of zebrafish transgenic lines via early morning injections
• Multiplexed Hybridization Chain Reaction (HCR) approaches in situ
• Single-cell and spatial transcriptomics approaches in mouse and zebrafish

Responsibilities: Daily lab operations

• Order and archive reagents and small equipment
• Manage stocks and organization of molecular and cellular biology reagents
• Organize and maintain lab databases, assign lab tasks to members
• Coordinate onboarding, access, and training of new lab members
• Maintain lab equipment, organize maintenance and repairs
• Represent the lab at institute meetings to optimize practices
• Coordinate with facility managers for outsourcing services (sequencing, genotyping, etc.)
• Manage communication with core facilities (e.g., PhenoZfish, ICM.Quant, Histomics, NeuroCEB, E3M FACS)

Time schedule and location

• No teleworking
• Early morning injections for genetic modifications require coming in early
• Occasional weekend work when animal care demands it
• Travel for training and conferences within Île-de-France and occasionally abroad