Job offer

European Commission; France; Sur place; EUR 40 000 - 65 000; Plein temps

Résumé du poste

L'Institut pour la Recherche et l'Innovation en Médecine recrute un professeur junior en recherche translationnelle pour des traitements innovants dans les maladies cardiaques. Le candidat aura une solide expérience postdoctorale et sera responsable de la gestion des projets de recherche en collaboration avec l'hôpital universitaire de Rouen.

Qualifications

• Expérience postdoctorale en recherche biomédicale.
• Capacité avérée à obtenir des financements compétitifs.

Responsabilités

• Coordonner et diriger la recherche translationnelle sur les maladies valvulaires.
• Renforcer les équipes d'enseignement au sein des départements de la santé.

Connaissances

Recherche indépendante

Communication en français

Formation

Doctorat

Description du poste

Institute for Research and Innovation in Biomedicine

Organisation/Company Inserm Department Institute for Research and Innovation in Biomedicine Research Field Medical sciences » Health sciences Pharmacological sciences » Other Biological sciences » Biology Medical sciences » Other Researcher Profile Recognised Researcher (R2) Positions Other Positions Country France Application Deadline 15 Sep 2025 - 12:00 (Europe/Paris) Type of Contract Temporary Job Status Full-time Hours Per Week 37 Offer Starting Date 15 Dec 2025 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

Project aim: Development of innovative treatments for the management of cardiac valvular diseases

The proposed tenure-Track Junior Professor Chair (CPJ) is part of the creation of the Alain Cribier Institute for Cardiac Valves in Rouen, Normandy, France. This strategic project, supported by Rouen University, Rouen University Hospital and Inserm, aims to promote Rouen’s excellence in research, education, clinical care, and communication specifically in the field of valvular heart diseases, particularly aortic stenosis. It builds on previous major clinical and translational initiatives, such as the FHU REMOD-VHF, the RHU STOP-AS, and the FHU CARNAVAL, which will conclude in 2025.

The Alain Cribier Institute aspires to become an international reference center for valvular diseases. Recruiting a talented junior researcher through the CPJ program will strengthen the institution’s research and innovation capacities, notably by intensifying international collaborations with leading laboratories and attracting top-level talent—thereby consolidating our scientific leadership in this domain. The long-term objective is to apply to a future IHU (University Hospital Institute) call for projects or an equivalent funding opportunity.

This CPJ aligns perfectly with the strategy of the University of Rouen Normandy, which supports academic excellence, translational research, and medical innovation, while promoting the international visibility of its teams. It will also contribute to the structuring of a research network on valvular diseases, the dissemination of high-level scientific publications, and active participation in large-scale European and international projects.

The CPJ candidate should have postdoctoral experience. They will be responsible for coordinating, leading, organizing, and energizing preclinical and translational research in the field of therapeutic innovation for the management of valvular heart diseases—particularly calcified aortic stenosis—aligned with Axis 2 of INSERM Unit 1096, in collaboration with the Cardiology and Cardiothoracic Surgery Departments of the Rouen University Hospital. Specifically, the CPJ candidate should have expertise in both cell culture and animal experimentation in relation to translational cardiovascular research. Their responsibilities will include:

• Managing the isolation and study of valvular cells
• Organotypic culture of murine, porcine, or human explanted valves
• In vivo studies in murine models of aortic stenosis, particularly in contexts of kidney failure induced by nephrectomy or metabolic disorders
• Establishing methodologies for studying bioprosthetic valve degeneration in rodents (subcutaneous implantation)
• Setting up a large animal model (sheep or pig) for in vivo investigation of the mechanisms and surgical or pharmacological treatments of aortic stenosis
• Leading and conducting biological studies in support of clinical trials and cohort studies carried out within the Institute.

Specific Requirements

• Documented ability to perform cutting-edge independent translational research in biomedical sciences (cardiovascular, biomedicine)
• Documented ability to obtain competitive funding as PI or co-PI
• Documented ability to communicate (oral, written) in French, due to the requirement of teaching (48 hours per year) expected of the holder of the CPJ.

Specifically, the recruited CPJ will be responsible for:

• Strengthening teaching teams across the departments of the Faculty of Health (Medicine, Pharmacy, Speech Therapy, Dentistry, Rehabilitation Sciences, etc.) for both mandatory and elective courses focused on the pathophysiology and therapeutic approaches to cardiovascular diseases
• Establishing a new University Diploma (DU/DIU) dedicated to valvular diseases
• Developing new teaching approaches based on simulation, in direct collaboration with the Medical Training Center (MTC) in Rouen https://www.mtc-rouen.com/
• Participating in teaching activities related to cell biology, molecular biology, and pathophysiology within the various academic units of the University of Rouen Normandy (Faculty of Science and Technology, ESITECH, IUT, etc.)

Languages FRENCH Level Excellent

Languages ENGLISH Level Good

Research Field Biological sciences » OtherMedical sciences » OtherPharmacological sciences » Other Years of Research Experience 4 - 10

Candidates must register their application and mandatory attach the documents constituting their file in .pdf format on the website of the Ministry of Higher Education, Research and Innovation (MESRI), via the ODYSSEE application.

Candidates must prepare a file composed of:

* an application form completed online

* a digital version of the following documents:

* a photo ID;

* a document attesting to the possession of a doctorate, as provided for in Article L.612-7 of the Education Code, or a diploma whose equivalence will be recognised in accordance with the procedure set out in 1° of Article 5 of the above-mentioned Decree of 17 December 2021; « report on the defence of the diploma produced;

* analytical presentation of the work, books, articles and achievements made on the model of the "CPJ application form" to be submitted as document 1 in the "titles and works";

* main titles and works indicated in the analytical presentation.

The administrative documents and the defence report written in whole or in part in a foreign language are accompanied by a translation into French, the conformity of which the candidate certifies on their honour. Otherwise, the file is declared unacceptable.

The translation of the analytical presentation as well as of the works, books, articles and achievements is optional.

All these documents must be submitted in digital version by the date indicated in the recruitment notice at the latest. Any application that is incomplete by the above-mentioned deadline is declared unacceptable.

Only persons previously selected on the basis of their application by the selection committee, whose composition will be made public before the start of its work, will be invited to the audition.

All applicants will access the status of their application and the results using the Odyssey candidate number and personal password.

Any candidate selected for one or more positions at the end of the procedure will have to commit on the dedicated application to hold the position.