Junior Biomolecular NMR Scientist for Drug Discovery

Novalix; Strasbourg; On-site; EUR 60,000 - 95,000; Full time

Job summary

Novalix in Strasbourg, France, seeks a dynamic NMR scientist to join the Structural Biology and Biophysics team under the Head of NMR, supporting pharmaceutical and biotechnology clients in their drug discovery programs.

You will design and perform advanced biomolecular NMR experiments, conduct ligand- and protein-observed assays, analyze complex data, develop new NMR methodologies, and present results to clients and internal teams.

Qualifications

• PhD in Structural Biology or Biophysics with strong theoretical and practical expertise in biomolecular NMR spectroscopy.
• Hands-on experience operating high-field NMR spectrometers (600, 700 and/or 800 MHz).
• Proven experience characterizing protein–ligand interactions using ligand- and/or protein-observed NMR approaches.
• Experience with multidimensional NMR experiments and resonance assignment strategies.

Responsibilities

• Design, perform and interpret advanced biomolecular NMR experiments for protein and protein-ligand characterization.
• Conduct ligand-observed and protein-observed NMR assays to support hit identification and fragment-based drug discovery.
• Perform multidimensional NMR analyses to characterize binding events and structural changes.
• Independently perform resonance assignments using state-of-the-art methodologies and computational tools.
• Analyze NMR datasets to provide structural and mechanistic insights for client projects.
• Contribute to development, validation and implementation of new NMR methodologies.
• Prepare protocols, SOPs and technical documentation.
• Present results to internal teams and clients through written and oral reports.
• Participate in troubleshooting and continuous improvement of NMR workflows and instrumentation.

Skills

Biomolecular NMR

NMR spectroscopy

High-field NMR

Fluent English

Education

PhD in Structural Biology

PhD in Biophysics

Tools

NMR software

Resonance assignment

Job description

Novalix in Strasbourg, France, seeks a dynamic NMR scientist to join the Structural Biology and Biophysics team under the Head of NMR, supporting pharmaceutical and biotechnology clients in their drug discovery programs.

You will design and perform advanced biomolecular NMR experiments, conduct ligand- and protein-observed assays, analyze complex data, develop new NMR methodologies, and present results to clients and internal teams.