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La CNRS recherche un Junior Chair axé sur les modifications chimiques de l'ARN, promouvant la science ouverte et l'interaction science-société. Le candidat retenu travaillera dans des laboratoires de renom à Toulouse ou Saclay, participant à des projets innovants et à l'enseignement supérieur.
The CNRS is a national multi-disciplinary research organization dedicated to scientific excellence and the advancement of knowledge. One of its objectives is to understand the involvement of non-genetic components in gene regulation and their impact on organism development and response to the environment. This Junior Chair aims to recruit a young scientist of international excellence in the field of RNA chemical modifications, aligning with the CNRS's strategic goals.
The selected candidate will work in either the MCD (Molecular, Cellular and Developmental Biology) laboratory in Toulouse or the IPS2 (Institute of Plant Sciences) in Saclay. MCD focuses on genome organization, cell division, and development in eukaryotes and archaebacteria, while IPS2 studies genetic and molecular mechanisms controlling plant growth, especially in relation to climate change. Both labs conduct integrative functional biology from molecules to whole organisms.
The research will focus on epitranscriptomic marks—over 160 types identified—affecting RNA maturation, stability, and function. These marks are crucial in regulating cellular activity in response to developmental and environmental signals, influencing organismal development, growth, and stress responses. The project will explore the roles of RNA modifications in eukaryotes, employing cutting-edge technologies, and can be developed in fungi, animals, or terrestrial plants.
Teaching responsibilities include participation in the teaching teams at Toulouse University, covering bachelor’s and master’s degrees in molecular and cellular biology, or at the doctoral level within the Ecole Doctorale Science du Végétal, and at the master level within the Ecole Universitaire de Recherche “Biologie Moléculaire des Plantes et des Microorganismes” at Paris Saclay University.
The CNRS promotes open science, aiming for 100% accessibility of research publications via HAL, and encourages data sharing and reusability. Research dissemination will include publications, patents, and software, as well as engagement with scientific communities, media, policymakers, the public, schools, and through events like conferences and summer schools. The project will also foster science-society interactions, informing public decision-making and initiating participatory science initiatives.
Applicants must hold a doctorate, PhD, or equivalent, with no restrictions on age or nationality. The CNRS ensures accessibility for people with disabilities, with accommodations as needed.