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Une opportunité passionnante se présente dans un laboratoire de recherche innovant, où un poste de Post-Doc est ouvert pour travailler sur des nanoparticules polyoxazoline. Ce projet ambitieux vise à développer des systèmes de délivrance de médicaments avancés, ciblant des applications en oncologie. Le candidat idéal aura une solide expérience en chimie organique et en synthèse de polymères, ainsi qu'une passion pour la recherche à l'interface de la chimie et de la médecine. Rejoignez une équipe dynamique et contribuez à des projets qui pourraient transformer le paysage du traitement du cancer.
Organisation/Company: UNIVERSITE ANGERS
Department: Human Resources - Recruitment
Research Field: Chemistry » Organic chemistry
Researcher Profile: Recognised Researcher (R2)
Positions: Postdoc Positions
Country: France
Application Deadline: 16 Apr 2025 - 23:59 (Europe/Paris)
Type of Contract: Temporary
Job Status: Full-time
Hours Per Week: 35
Offer Starting Date: 1 Jun 2025
Is the job funded through the EU Research Framework Programme? Not funded by a EU programme
Is the Job related to staff position within a Research Infrastructure? No
A Post-Doc position is available in the MINT laboratory of the University of Angers (UMR INSERM U1066 // UMR CNRS 6021) and this project will be developed in collaboration with MOLTECH-Anjou Laboratory of the University of Angers (UMR CNRS 6200).
This project focuses on the development of polyoxazoline-based nanoparticles for advanced drug delivery and diagnostic applications, particularly in cancer treatment. The work will involve the design and synthesis of novel multifunctional polymeric materials for drug delivery systems (DDS), integrating targeted functionalization and stimulus-responsive properties. These systems aim to enhance in vitro and in vivo imaging while ensuring precise drug release at specific disease sites, improving therapeutic efficacy and minimizing side effects.
A key aspect of the project is the development of polymeric-based nanoparticles (NPs) and Lipid NanoCapsules (LNCs) incorporating functionalized polyoxazolines. These hybrid nanocarriers will be engineered to integrate fluorescent probes for imaging, targeting molecules for selective delivery, and prodrug fragments for controlled drug activation. Their potential in theranostic applications—combining therapy and diagnostics—will be extensively explored.