Investigation and Development of Analytical Methods to Characterize and Quantify Physico-chemic[...]

TN France; France; Sur place; EUR 30 000 - 50 000; Plein temps

Résumé du poste

An innovative research opportunity awaits a highly motivated PhD candidate to explore the critical field of physico-chemical incompatibility between drugs. This role focuses on developing analytical methods to characterize and quantify drug incompatibilities, significantly impacting pharmaceutical formulation and drug development. The successful candidate will engage in cutting-edge research, collaborating with interdisciplinary teams to enhance drug safety and efficacy. If you are passionate about advancing pharmaceutical sciences and eager to contribute to groundbreaking research, this position offers a unique chance to make a meaningful difference in the industry.

Qualifications

• Master's degree in relevant field required.
• Strong knowledge of drug development processes essential.

Responsabilités

• Conduct literature reviews on drug incompatibility research.
• Design and execute experimental protocols for drug interactions.
• Analyze and interpret data to propose innovative solutions.

Connaissances

Analytical Techniques

Spectroscopy

Chromatography

Thermal Analysis

Pharmaceutical Sciences

Drug Development

Communication Skills

Formation

Master's Degree in Pharmaceutical Sciences

Master's Degree in Organic Chemistry

Master's Degree in Analytical Chemistry

Outils

Spectroscopic Analysis

Chromatographic Techniques

Thermal Profiling

Description du poste

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Investigation and Development of Analytical Methods to Characterize and Quantify Physico-chemical Incompatibility between Drugs, Auvergne-Rhône-Alpes, France

Job Description:

Thesis Summary

We are seeking a highly motivated and skilled PhD candidate to join our research team to explore the fascinating field of physico-chemical incompatibility between drugs. This research aims to investigate and develop innovative analytical methods that enable the characterization and quantification of drug incompatibilities, ultimately contributing to the improvement of pharmaceutical formulation and drug development processes.

The objective of this thesis is to investigate the intricate interactions and transformations that occur when multiple drugs are combined within a single formulation or delivery system. The successful candidate will have the opportunity to work on advancing our understanding of physico-chemical incompatibilities, focusing on identifying the underlying mechanisms, predicting potential drug-drug interactions, and developing analytical tools to evaluate the extent of incompatibility.

Key Responsibilities

• Conduct an in-depth review of existing scientific literature to identify the current state-of-the-art in drug incompatibility research and analytical techniques.
• Design and execute experimental protocols to investigate the physico-chemical interactions between drugs, utilizing a combination of spectroscopic, chromatographic, and thermal analysis techniques.
• Develop novel analytical methods, including spectroscopic analysis, chromatography, and thermal profiling, to characterize and quantify drug incompatibilities in various formulations and delivery systems.
• Analyze and interpret experimental data to gain insights into the mechanisms underlying drug incompatibilities, and propose innovative approaches to predict and mitigate adverse interactions.
• Collaborate with interdisciplinary teams to integrate the developed methods into the drug development process, working closely with formulation scientists and pharmaceutical engineers.
• Prepare scientific reports, present research findings at conferences, and publish research outcomes in reputable scientific journals, contributing to the advancement of knowledge in the field.

Requirements

• A Master's degree in pharmaceutical sciences, organic chemistry, or analytical chemistry.
• Strong knowledge of pharmaceutical sciences and drug development processes.
• Experience with analytical techniques such as spectroscopy, chromatography, and thermal analysis.
• Experience in the private sector is highly welcomed.
• Excellent written and verbal communication skills in French and English.
• Ability to work independently and as part of a collaborative research team.