Lead researcher position on autoimmune diseases

French National Institute for Health Research (INSERM); Paris; Sur place; EUR 45 000 - 75 000; Plein temps

Résumé du poste

An established industry player is seeking a talented researcher to join their innovative i3 Laboratory in Paris. This position focuses on advancing the understanding of immune system dysregulation through the development of cutting-edge computational models and experimental research. The successful candidate will leverage extensive datasets to propose novel therapeutic strategies, contributing to groundbreaking research in the field of immunology. If you are passionate about translating complex data into meaningful insights and have a strong background in both experimental and computational methodologies, this role offers an exciting opportunity to make a significant impact in health research.

Qualifications

• Strong background in Immunology with experience in omics technologies.
• Skills in cellular and molecular biology or computational biology.

Responsabilités

• Propose innovative projects for identifying biomarkers and therapeutic targets.
• Develop computational models and algorithms for immune system research.

Connaissances

Immunology

Computational Modeling

Cellular Biology

Molecular Biology

Omics Technologies

Formation

PhD in Immunology or related field

Description du poste

The proposed position at the i3 Laboratory will be seamlessly integrated into the research and training endeavors of the laboratory and affiliated institutions. The primary objective for the candidate will be to propose innovative projects aimed at identifying biomarkers and novel therapeutic targets through either the development of advanced computational models and algorithms to uncover fundamental mechanisms underlying immune system dysregulation or the design of translational research projects aimed at testing and validating new therapeutic strategies. A central aspect of this role will involve building upon the extensive datasets already generated by the i3 Laboratory. These datasets include comprehensive immunophenotyping of blood cells, full transcriptome and T-cell receptor repertoires of regulatory T-cells, effector T-cells, and CD8 T-cells, as well as gut microbiome data from a cohort of 900 patients with autoimmune and inflammatory diseases and healthy volunteers. Additionally,meticulous metadata containing accurate clinical descriptions of the patients are available.
Candidate should possess a strong background in Immunology and substantial professional experience with state-of-the-art omics technologies together with experimental skills in cellular and molecular biology or in modeling and computational biology.