DNA Origami: Tunable Kinase Assemblies (6mo internship)

INSERM DR Grand Ouest; France; Sur place; EUR 5 800 - 7 100; Plein temps

Résumé du poste

INSERM DR Grand Ouest in Rennes, France, invites applications for a Master internship to support a PhD project on protein–DNA nanostructures using DNA origami. Remuneration is 580€ net/month; duration is 6 months from January to July 2027.

You will express and purify the protein kinase N-terminus, assemble and purify DNA origami structures, bioconjugate proteins, validate with AFM, and evaluate enzymatic activities with established assays.

Qualifications

• Background in chemical biology, biochemistry, biophysics, molecular biology or related life sciences.
• Motivated student from national and international community.

Responsabilités

• Express, purify and functionalize the protein kinase N-terminus.
• Assemble and purify DNA origami structures.
• Bioconjugate proteins on DNA origami using DNA hybridization.
• Validate by AFM microscopy of the protein–DNA nanostructure.
• Evaluate enzymatic activities using established biochemical assays.

Connaissances

English (Good)

Molecular biology

Formation

Master Degree or equivalent

Outils

DNA origami

Description du poste

INSERM DR Grand Ouest in Rennes, France, invites applications for a Master internship to support a PhD project on protein–DNA nanostructures using DNA origami. Remuneration is 580€ net/month; duration is 6 months from January to July 2027.

You will express and purify the protein kinase N-terminus, assemble and purify DNA origami structures, bioconjugate proteins, validate with AFM, and evaluate enzymatic activities with established assays.