Biology Lead, Drug Discovery (Hit-to-Lead)

Aqemia; Paris; Ibrido; EUR 120.000 - 180.000; Tempo pieno

Descrizione del lavoro

AQEMIA in Paris and London is seeking a Biology Lead to guide small molecule programs from hit to lead and into candidate nomination.

You will work with medicinal chemists, computational scientists, and AI specialists in a fast-paced, collaborative environment across oncology and CNS, with exposure to in vivo pharmacology.

AQEMIA offers flexible work arrangements including up to two remote days per week and a strong, growing pipeline backed by major investors.

Competenze

• PhD in biological sciences (e.g., pharmacology, molecular biology, chemical biology, biochemistry).
• Typically ~5+ years of industry experience in small molecule drug discovery.
• Hands-on experience progressing projects through hit-to-lead or lead optimization.
• Strong expertise in oncology or CNS and wet-lab biology.

Mansioni

• Act as biology lead on a drug discovery project, driving its biological strategy and progression from hit-to-lead through lead optimization
• Design, implement, and maintain screening cascades to generate high-quality in vitro and in vivo data
• Sign off biological experiments and collaborate with external CROs on study design, model selection, and data quality
• Analyse and interpret biological and pharmacological data, building data packages and recommendations for DDS leadership
• Identify scientific risks early and highlight opportunities to accelerate project progression
• Bring independent ideas on project direction and differentiation from competitors
• Contribute to target identification and new project ideation across oncology and CNS
• Foster cross-functional collaboration, integrating biology with chemistry, modeling, and platform teams

Conoscenze

In vitro pharmacology

Screening cascade design

Oncology/CNS expertise

Scientific communication

Biology wet lab experience

Project leadership

Formazione

PhD in biological sciences

Descrizione del lavoro

AQEMIA in Paris and London is seeking a Biology Lead to guide small molecule programs from hit to lead and into candidate nomination.

You will work with medicinal chemists, computational scientists, and AI specialists in a fast-paced, collaborative environment across oncology and CNS, with exposure to in vivo pharmacology.

AQEMIA offers flexible work arrangements including up to two remote days per week and a strong, growing pipeline backed by major investors.