Senior Medicinal Chemist — AI-Driven Drug Discovery

Aqemia; Paris; Hybride; EUR 90 000 - 140 000; Plein temps

Avantages offerts par ce poste

Hybrid work

Up to two remote days per week

Résumé du poste

AQEMIA is a drug invention company with a strong focus on AI-assisted design and first-principles chemistry. We seek a Medicinal Chemist to drive lead optimization and creativity in early drug discovery, working at the interface of chemistry and biology.

You will collaborate across disciplines in Paris and London, leveraging QEMI technology to design novel molecules and advance them toward preclinical candidates, while contributing to patents and project planning.

Qualifications

• PhD in synthetic or organic chemistry completed.
• 10 years of industrial drug discovery experience.
• Strong track record in organic synthesis and compound design.
• Interest in AI-driven drug design.
• Ability to work with interdisciplinary teams.
• Familiarity with molecular modeling and ADME optimization.
• Excellent problem-solving and communication skills.

Responsabilités

• Collaborate closely with the technology platform to challenge and improve it and to design innovative molecules.
• Optimize lead compounds and transform them into drug candidates using our technology.
• Autonomously execute and interpret complex activities to identify pharmaceutical candidates.
• Prepare and follow tasks given to CROs, including synthesis of novel small molecules and generation of biological data.
• Follow and drive programs in medicinal chemistry.
• Contribute to patent filings.
• Maintain clear, accurate written records of decisions and progress.
• Collaborate with project managers to establish timelines and costs.

Connaissances

Organic synthesis

Drug design

AI-driven design

Interdisciplinary teamwork

SAR analysis

ADME optimization

Scientific communication

Formation

PhD in synthetic or organic chemistry

Description du poste

AQEMIA is a drug invention company with a strong focus on AI-assisted design and first-principles chemistry. We seek a Medicinal Chemist to drive lead optimization and creativity in early drug discovery, working at the interface of chemistry and biology.

You will collaborate across disciplines in Paris and London, leveraging QEMI technology to design novel molecules and advance them toward preclinical candidates, while contributing to patents and project planning.