2017/09/13 – Postdoctoral position (12 Months) : « Development of a bimodal Brillouin/Raman mic[...]

France Life Imaging; Grenoble; Sur place; EUR 30 000 - 40 000; Plein temps

Résumé du poste

Un laboratoire de biophysique recherche un chercheur postdoctoral pour développer et caractériser un nouveau modèle de bioimagerie en couplant la spectroscopie de Brillouin et Raman. Le candidat doit avoir un doctorat en sciences physiques ou ingénierie et une solide expérience en optique. La maîtrise du français et/ou de l'anglais est requise.

Qualifications

• Connaissances en optique physique appliqué aux sciences de la vie.
• Expérience réussie dans le contrôle d'instruments optiques.
• Intérêt pour les applications de l'optique en sciences de la vie.

Responsabilités

• Développer un spectromètre Brillouin couplé à un microspectromètre Raman.
• Caractériser l'instrument sur des systèmes modèles.
• Coordonner les interactions entre LPCV et LISA.

Connaissances

Optique physique

Spectroscopie Raman

Spectroscopie Brillouin

Communication claire

Formation

PhD en sciences physiques ou ingénierie

Description du poste

Overview

Type de structure : The Laboratory of Physics of Cytoskeleton and Morphogenesis (LPCV) at CEA Grenoble has an opening for setting up and characterizing a novel bioimaging modality combining Brillouin and Raman Spectroscopy. This is an interdisciplinary project between LPCV and the Laboratory of Imaging and Acquisition Systems (LISA) of CEA Grenoble, starting January 2018.

Contexte et mission

Brillouin microscopy allows non-invasive measurements of the visco-elastic properties of cells and tissue on the micrometer scale, while Raman microscopy gives complementary biochemical information. Such measurements have applications in the study of cytoskeleton organization, and for novel diagnostic tools based on following early mechanical and biochemical tissue alterations.

The postdoctoral scholar will be responsible for developing and coupling a Brillouin spectrometer to the Raman micro-spectrometer of LISA. This includes optical system development, instrument control and numerical data processing. He/She will characterize the instrument on model systems prepared at LPCV, and move forward to first in-cellulo experiments. The successful candidate is expected to coordinate the interaction between LPCV and LISA.

Lieu

Laboratory of Physics of Cytoskeleton and Morphogenesis, CEA, Grenoble, France.

Diplômes requis

PhD degree in physical sciences, or engineering

Compétences requises

• Solid background in physical optics, ideally on Raman or Brillouin spectroscopy for life sciences.
• Successful experience working at optical bench (including instrument control).
• Strong interest for applications of optics in the life sciences.
• Fluent in French, and/or English (oral and written), clear and effective communication skills.

Contact

Interested candidates should contact Jean-Charles Baritaux ( [e-mail]).