Chemical Biologist, Hit-Finding & Modality Discovery

Orion Corporation; Espoo; Presencial; EUR 70.000 - 110.000; Jornada completa

Descripción de la vacante

Orion Pharma in Espoo, Finland is seeking a curious chemical biologist to join the Hit Finding team within the Structural Biology and Discovery Technologies unit. You will apply chemical and biological thinking to early drug-discovery questions and grow alongside experienced colleagues, expanding into biochemistry, biophysics, and molecular pharmacology.

You will work with the Chemical Biology Lead and Chemistry Leads, shaping modality strategies and project-specific hit-finding plans,

Formación

• PhD in chemical biology, medicinal chemistry, biochemistry, or closely related field.
• Strong chemical literacy and understanding of how molecular structure relates to biological data.
• Clear written and oral English; ability to work in multidisciplinary teams.

Responsabilidades

• Support modality and hit-finding strategies for early drug-discovery projects.
• Gather and integrate information on targets, ligands, tools, assays, and literature to inform decisions.
• Design biochemical/biophysical assay cascades for hit finding and mechanism studies.
• Define protein constructs, controls, and orthogonal methods with internal/external partners.
• Review study plans and data with CROs and partners; identify follow-up experiments.
• Select and apply chemical/biological tools to assess target engagement and modality feasibility.
• Help define structural biology questions required to define modality strategy and interpret assay data.

Conocimientos

Chemical biology

Collaboration

Assay interpretation

Data analysis

Educación

PhD in chemistry/biochemistry/chemical biology

Herramientas

SPR

NMR

DSF

ITC

Descripción del empleo

Orion Pharma in Espoo, Finland is seeking a curious chemical biologist to join the Hit Finding team within the Structural Biology and Discovery Technologies unit. You will apply chemical and biological thinking to early drug-discovery questions and grow alongside experienced colleagues, expanding into biochemistry, biophysics, and molecular pharmacology.

You will work with the Chemical Biology Lead and Chemistry Leads, shaping modality strategies and project-specific hit-finding plans,