Senior Scientist (CNS)

SpliceBio; Barcelona; Presencial; EUR 90.000 - 130.000; Jornada completa

Descripción de la vacante

SpliceBio seeks a Principal Scientist to lead CNS AAV gene therapy research, mentor scientists, and guide project execution during maternity leave cover.

You will design complex experiments, analyze data, and communicate findings to senior leadership, ensuring continuity of CNS pre-clinical activities and maintaining strategic direction.

Formación

• PhD or equivalent experience in a scientific discipline; field preferred: Neuroscience, Gene Therapy, Molecular Biology, Virology, or related.
• Minimum 5 years in relevant biotech/pharma roles with extensive CNS gene therapy experience.
• Strong background in AAV-based gene therapy and related assays.

Responsabilidades

• Lead experimental design and execution for CNS AAV projects, guiding in vivo and in vitro studies.
• Mentor Scientists and Technicians, supporting development and scientific growth.
• Coordinate multidisciplinary pre-clinical efforts, manage milestones and resources.

Conocimientos

Leadership

Data analysis

Project management

Communication

Mentoring

Cross-functional collaboration

Educación

PhD in a scientific discipline

Descripción del empleo

The Principal Scientist plays a pivotal role in advancing scientific research and guiding project execution. In addition to managing complex experiments and contributing to research strategy, he/she provides mentorship to Scientists and Laboratory Technicians, sharing expertise and supporting their development. His/her deep scientific knowledge and experience in CNS AAV gene therapy contribute to innovation, project continuity, and high-quality results. He/she fosters collaboration, promotes best practices, and helps create a positive, focused research environment.

This position is a fixed-term role to provide maternity leave cover ensuring continuity of scientific leadership, project delivery, and team support during the temporary absence of the substantive post holder.

Key Responsibilities

Experimental Design and Execution

• Designing and executing complex laboratory in vitro and in vivo experiments, following established protocols and procedures. Your expertise will contribute to the development of research methodologies, ensuring the highest standards of scientific rigor and accuracy.
• Design and implement novel laboratory protocols.
• Taking responsibility for the successful planning, execution, and completion of research projects. You will coordinate efforts across interdisciplinary teams, set project milestones, and manage resources effectively to ensure timely delivery.

Data Analysis, Conclusion, And Reporting

• Applying advanced statistical analysis methods and data visualization techniques to analyse and interpret experimental data.
• Drawing meaningful conclusions and communicating research findings effectively to internal and external stakeholders
• Provide critical insights for the VP and Director of the department.
• Author high-impact reports, publications.
• Participate in project meetings and represent the CNS team when required.

Collaboration And Project Support

• Act as the scientific liaison between the VP-Pre Clinical and the laboratory team during the maternity&paternitity leave.
• Provide day-to-day scientific guidance to Scientists and Technicians in the CNS team.
• Ensure continuity of CNS pre-clinical activities and project execution.
• Support experimental planning, data review, troubleshooting, and decision-making.
• Play a key role in shaping the overall scientific strategy with the collaboration of others scientist, principal scientist and managers/directors.
• Collaborating with internal and external stakeholders, including academic researchers, industry partners, and regulatory bodies.
• Building and maintaining collaborative relationships to foster knowledge exchange, access additional expertise, and drive research collaborations.
• Monitor project timelines, identify risks, and help achieving milestones.

Continuous Learning

• Staying update with the latest scientific advancements and technological innovations in the field.
• Lead scientific sessions and workshops.

Training And Supervision

• Lead the training and development of technicians.
• Mentor and guide junior and senior scientists.

Qualifications

• PhD or relevant experience in a scientific discipline, preferred in Neuroscience, Gene Therapy, Molecular Biology, Virology, or a related field.
• Minimum 5 years of experience in relevant biotech/pharmaceutical industry roles with extensive experience in CNS gene therapy.
• In addition to familiarity in CNS research, a strong background in AAV-based gene therapy (AAV vector biology, functional assays, or related areas).

KEY COMPETENCIES

• Proven experience leading or coordinating multidisciplinary pre-clinical projects.
• Highly proficient in analyzing complex data independently, applying advanced techniques, and identifying patterns or insights.
• Excellent at managing multiple tasks and deadlines, demonstrating efficiency and prioritization and cross-functional interactions.
• Strong attention to details.
• Strong communication skills and ability to interact with internal stakeholders and external collaborators.
• Strong ability to manage multiple tasks efficiently while maintaining a well-organized environment.
• Excellent scientific judgment and strong problem-solving skills, with the ability to address complex scientific challenges and propose innovative solutions.
• Strong ability to work effectively within a team, fostering collaboration and mentoring junior staff.
• Flexibility in adjusting to changing tasks, priorities, and research needs in a dynamic environment.
• Strong adaptability to fast-paced environment, matrix organizations.
• Comfortable making scientific decisions independently while maintaining alignment with project objectives.