Senior Bioinformatician (Location: Valencia/Belgrade/Remote)

CENTOGENE GmbH; Valencia; A distancia; EUR 50.000 - 80.000; Jornada completa

Descripción de la vacante

A leading company in bioinformatics seeks a Senior Bioinformatician to enhance their cloud-based platform, CentoDX. The ideal candidate will design and implement data analysis pipelines, optimize algorithms, and work closely with clinical teams to ensure high-quality diagnostics. This role requires a Ph.D. or Master's, along with significant experience in bioinformatics and software development.

Formación

• Ph.D. with 5+ years of experience or Master's with 8+ years.
• Expertise in Python and bioinformatics software development.
• Hands-on NGS data analysis experience, particularly RNA-seq, WES/WGS.

Responsabilidades

• Design and maintain bioinformatics analysis pipelines.
• Lead the development and automation of diagnostic workflows.
• Collaborate with cross-functional teams to meet scientific needs.

Conocimientos

Python

NGS data analysis

Software engineering principles

Version control (Git)

Organizational skills

Problem-solving skills

Educación

Ph.D. in Bioinformatics, Computational Biology, Computer Science, or related field

Master's degree

Herramientas

AWS

MySQL

Descripción del empleo

Permanent employee,Full-time· Spain - Valencia, Serbia - Belgrade, Remote

We are seeking a highly skilled and experienced Senior Bioinformatician to join our Bioinformatics team, supporting the development of CentoDX, our advanced cloud-based bioinformatics platform. In this role, you will lead the design and implementation of robust, scalable data analysis pipelines and actively contribute to algorithm optimization, data integration, and automation across our clinical diagnostics workflows.

• Design, develop, and maintain bioinformatics analysis pipelines for sequence alignment, variant calling, annotation, and other data processing pipelines.

• Lead the upgrade and enhancement of genomic bioinformatic data and pipelines, ensuring compatibility and accuracy
• Maintain and enhance internal MySQL databases and ensure regular updates from external data sources (e.g., gnomAD, ClinVar, HGMD, RefSeq)
• Oversee the continual update and validation of gene, transcript, and functional annotation pipelines in line with best practices
• Drive development and refinement of bioinformatics algorithms to improve diagnostic accuracy and data interpretation
• Lead the automation of tertiary analysis pipelines, ensuring scalability, reproducibility, and high-throughput performance
• Collaborate closely with the Dry lab teams to translate scientific requirements into production-ready tools and support clinical decision-making
• Identify and implement strategies for continuous improvement in data workflows, system performance, and data quality

Ph.D. in Bioinformatics, Computational Biology, Computer Science, or related field with 5+ years of experience; or Master’s degree with 8+ years of relevant industry experience

Proven expertise in Python for bioinformatics software and pipeline development

Hands-on experience in NGS data analysis (e.g., RNA-seq, WES/WGS, variant interpretation)

Strong understanding of genomic data standards, formats (VCF, BED, GTF), and bioinformatics best practices

Demonstrated experience working in cloud-based environments (AWS preferred) with tools like AWS Batch, Lambda, or Step Functions

Experience with relational databases, particularly MySQL, for data management and integration

Solid understanding of software engineering principles, version control (Git), and reproducible research workflows

Strong organizational skills with the ability to prioritize tasks, meet deadlines, and align with company objectives

Excellent problem-solving skills and ability to work collaboratively in cross-functional teams

With employees from over 50 nations, CENTOGENE is a truly international company with offices is in Rostock, Berlin, Delhi, Boston, Valencia, Belgrade, and São Paulo.

We were born to help diagnostic patients with rare disease and today we evolved to help patients of all clinical specialties to make bold progress with guided solutions for physicians, their patients and pharma partners.