R&D Researcher Cell-line development

HIPRA; Aiguaviva; On-site; EUR 60,000 - 80,000; Full time

Job summary

Responsibilities include literature reviews, protocol design for accelerated cell line generation, data analysis, vector construction, and collaboration with cross-functional teams to integrate automated systems, while maintaining regulatory compliance.

Qualifications

• Proven experience in mammalian cell culture and genetic engineering for recombinant protein expression.
• PhD in Biotechnology, Molecular Biology, or related field.
• Academic and ideally pharmaceutical industry experience.
• Knowledge of vector design and optimization strategies.
• Familiar with antibody biology and expression systems.
• Proficiency in spoken and written English for daily tasks.

Responsibilities

• Conduct literature reviews and evaluate state-of-the-art technologies for targeted and semi-targeted integration strategies.
• Design and optimize experimental protocols for accelerated cell line generation.
• Supervise and monitor laboratory experiments, ensuring data integrity and reproducibility.
• Analyze experimental results and propose improvements to workflows.
• Design and construct expression vectors, including optimization of regulatory elements.
• Collaborate with cross-functional teams to integrate high-throughput and automated systems.
• Document all activities in compliance with internal and regulatory standards.

Skills

Mammalian cell culture

Genetic engineering

Antibody biology

Expression systems

English proficiency

Education

PhD in Biotechnology or Molecular Biology

Tools

Vector design

Regulatory element optimization

Job description

HIPRA is a pharmaceutical and biotechnological company focused on prevention and diagnosis for animal and human health, with a broad range of highly innovative vaccines and an advanced diagnostic service.

HIPRA has a solid international presence in more than 40 countries, with its own subsidiaries, 11 diagnostic centres and 6 production plants strategically located in Europe (Spain) and America (Brazil). Research and Development constitute the core of its knowledge.

HIPRA dedicates 15% of its annual turnover to R&D activities that concentrate on the creation and application of the latest scientific advances to the development of the highest quality innovative vaccines. To give added value to its vaccination experience, the company also develops medical devices and traceability services.

HIPRA is seeking a highly motivated R&D Scientist to join our Cell Line Development team, based in Hipra Campus (Aiguaviva – Girona)

This role requires strong expertise in genetic engineering for recombinant protein expression in mammalian cells (preferably CHO) and a solid understanding of antibody design and production.

We are looking for candidates who:

• Have proven experience in mammalian cell culture and genetic engineering for recombinant protein expression
• Hold a PhD in Biotechnology, Molecular Biology, or related field
• Bring both academic and (ideally) pharmaceutical industry experience.
• Hace knowledge of vector design and optimization strategies.
• Are familiar with antibody biology and expression systems
• Have a Proficiency level of spoken and written English for daily task development.
• Are able to work to work independently and lead a specific work package, with strong analytical and creative skills, as well as planning, follow-up, and proactivity.

At Hipra you will find:

• Continuous learning.
• A rapidly expanding multinational company.
• A multicultural environment open to new ideas.
• Long term job positions.

Main responsibilities:

• Conduct literature reviews and evaluate state-of-the-art technologies for targeted and semi-targeted integration strategies.
  • Design and optimize experimental protocols for accelerated cell line generation.
• Supervise and monitor laboratory experiments, ensuring data integrity and reproducibility.
  • Analyze experimental results and propose improvements to workflows.
  • Design and construct expression vectors, including optimization of regulatory elements.
  • Collaborate with cross-functional teams to integrate high-throughput and automated systems.
  • Document all activities in compliance with internal and regulatory standards.