Postdoctoral Position in Regulation of Cell Behavior via Substrate Stiffness Modulation

PhDFinder; Lérida; Presencial; EUR 30.000 - 45.000; Jornada completa

Descripción de la vacante

Un groupe de recherche à la Universitat Politècnica de Catalunya offre un poste postdoctoral pour participer au projet BioFLEX, axé sur la modélisation de la rigidité des substrats dans la régénération tissulaire. Les candidats doivent avoir une expérience en culture cellulaire et en techniques moléculaires. Ce poste vise à comprendre l'impact de la rigidité sur le comportement cellulaire afin d'améliorer la réparation des tissus.

Formación

• Expérience avec des études de culture cellulaire sur des substrats 2D/3D.
• Compétences en techniques moléculaires telles que PCR et ELISA.
• Connaissance en mécano-biolgiologie est un atout.

Responsabilidades

• Réaliser des études sur la culture cellulaire avec des membranes en céramique nanofibres.
• Analyser les effets de la rigidité des substrats sur l'adhésion cellulaire.
• Collaborer au sein d'une équipe multidisciplinaire en ingénierie des biomatériaux.

Conocimientos

Culture cellulaire

Analyse de données quantitatives

Biologie moléculaire

Microscopie confocale à fluorescence

Educación

Doctorat en ingénierie biomédicale ou discipline connexe

Descripción del empleo

Hace 2 días Sé de los primeros 25 solicitantes

University: Universitat Politècnica de Catalunya (UPC) – BarcelonaTECH

Country: Spain

Deadline: 2025-07-31

Fields: Biological Engineering, Biomedical Engineering, Cell Biology, Materials Science, Tissue Engineering

Postdoctoral Position – Regulation of Cell Behavior via Substrate Stiffness Modulation

The Biomaterials, Biomechanics and Tissue Engineering research group at the Materials Science and Engineering Department of the Universitat Politècnica de Catalunya (UPC) – BarcelonaTECH invites applications for a full-time postdoctoral researcher to participate in the BioFLEX Project. This project is dedicated to the development of flexible nanofibrous hydroxyapatite ceramic membranes and scaffolds with tunable stiffness for tissue regeneration, aiming to elucidate the relationship between mechanical stiffness and cellular behavior to enhance tissue repair.

Key Responsibilities

– Conduct cell culture studies using nanofibrous ceramic membranes and scaffolds with variable stiffness.

– Investigate the effects of substrate stiffness on cell adhesion, proliferation, and differentiation.

– Perform and analyze results from molecular biology techniques and quantitative data analysis.

– Collaborate within a multidisciplinary team in the Biomaterials, Biomechanics and Tissue Engineering group.

Requirements

– Experience with cell culture, including adhesion, proliferation, and differentiation assays on 2D/3D substrates.

– Proficiency in molecular biology techniques such as PCR, digital PCR, electrophoresis, ELISA, plasma nucleic acid isolation, and flow cytometry.

– Experience with fluorescence confocal microscopy methods and quantitative data analysis.

– Background in mechanobiology is highly advantageous.

Application Process

Interested candidates should submit the following documents to [e-mail]:

– Motivation letter

– Curriculum Vitae (CV)

– Names and contact details of two referees

Contract Details

– Full-time, 1-year contract

For further information, please visit: https://biomaterials.upc.edu/cen

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