POSTDOCTORAL POSITION FOR ERC PROJECT hASTROCURE

Achucarro Basque Center for Neuroscience; País Vasco; Presencial; EUR 30.000 - 45.000; Jornada completa

Descripción de la vacante

A leading neuroscience institution in Spain is seeking a Post-doctoral Researcher to join a project focused on Alzheimer's disease. The successful candidate will work with human astrocytes and develop innovative in vitro models. A PhD in a related field is required, along with experience in hiPSC differentiation and bioinformatics. This is a full-time position starting on 1 January 2026 with responsibilities including maintaining cell cultures and analyzing data.

Formación

• PhD and excellent academic record required.
• Experience with mouse models and bioinformatics preferred.
• Strong analytical skills essential.

Responsabilidades

• Maintain human induced pluripotent stem cells.
• Analyze chimeric mouse models of Alzheimer's.
• Prepare reports and presentations.

Conocimientos

hiPSC differentiation

Programming (R, Python, MATLAB)

Immunofluorescence

Data analysis

English proficiency

Teamwork

Educación

PhD in Neuroscience, Cell Biology, or related field

Descripción del empleo

Overview

Position: Post-doctoral Position

Deadline: 15 November 2025

Employment Start Date: 1 January 2026

Country: Spain

Institution: Achucarro Basque Center for Neuroscience

Department:

Description:

The Arranz Lab – Laboratory of Humanized Models of Disease at Achucarro Basque Center for Neuroscience (Spain) is seeking a Postdoctoral Researcher to join hASTROCURE, a project funded by the European Research Council (ref ERC-2024-COG-01171591). Our lab focuses on understanding the complex role of human astrocytes in Alzheimer’s disease (AD). Using cutting-edge stem cell technologies, humanized in vitro models, and chimeric mice, our research aims to dissect how human astrocytes contribute to AD onset and progression. We are part of a vibrant neuroscience community and collaborate closely with national and international partners.

Position Overview: The successful candidate will focus on understanding the reactive states of human astrocytes, and how they contribute to AD, using humanized in vitro models and chimeric AD mice. The candidate will work closely with experts in bioinformatics & spatial omics. It is a full-time position, starting the 1st January 2026.

Responsibilities

• Culture, maintenance, and amplification of human induced pluripotent stem cells (hiPSCs), and derived neural progenitors and astrocytes.
• Design and perform experiments using hiPSC-derived astrocytes and other CNS cell types.
• Establish, maintain, and analyze chimeric mouse models of AD.
• Perform molecular, cellular and imaging assays (sample processing, immunofluorescence, microscopy, etc).
• Analyze and interpret data; prepare reports, manuscripts, and presentations.

Qualifications

• A PhD and excellent academic record in Neuroscience, Cell Biology, Bioinformatics, or related field.
• Previous experience in hiPSC differentiation to neural cells and astrocytes, and in vivo work (mouse models).
• Programming experience (e.g., R, Python, MATLAB) and familiarity with relevant bioinformatics pipelines.
• Experience with sample processing, immunofluorescence, and microscopy.
• Strong analytical, quantitative and time-management skills.
• Good/excellent written and spoken English; ability to write scientific reports and papers.
• Strong motivation for learning; ability to work independently and as part of a team.
• Prior experience with Alzheimer’s disease models and glia/astrocyte biology.
• Prior track record of peer-reviewed publications in relevant fields.
• Prior experience supervising students.

How to Apply

To apply, please send the following documents written in English indicating “Postdoc candidate_Surname” to [e-mail] :

• A detailed CV including list of publications/congress participation, statement of achievements (200 words), previous positions, the degree’s academic record and certificates (including animal experiments training).
• A cover letter explaining your research interests, relevant experience & how you would contribute to our lab.
• Contact details of 2-3 referees (including PhD supervisor)