Postdoctoral Fellow in Colorectal Cancer (CRC)

Findauniversity Ltd.; España; Presencial; EUR 30.000 - 45.000; Jornada completa

Descripción de la vacante

IRB Barcelona is seeking a motivated Postdoctoral Fellow in Colorectal Cancer to join a leading lab focused on understanding immune-evasion mechanisms in metastatic CRC. This role involves cutting-edge research in collaboration with top laboratories, requiring a strong background in tumor immunology and relevant skills in molecular biology.

Formación

• Experience with organoid culturing is a plus.
• At least one first-author research paper during PhD is preferred.
• Experience with big data analyses and coding in R/Python prioritized.

Responsabilidades

• Develop a project on immune-evasion mechanisms in metastatic CRC.
• Collaborate with leading laboratories and apply state-of-the-art technologies.
• Conduct in vivo immune cell dynamics tracking at a single-cell level.

Conocimientos

Tumour Immunology

Cell Culture

Molecular Biology

FACS Analyses

In Vivo Experiments

Analytical Skills

Problem-Solving Skills

Fluency in English

Educación

Doctoral degree in Life Sciences

Descripción del empleo

Postdoctoral Fellow in Colorectal Cancer (CRC)

IRB Barcelona is seeking an enthusiastic, motivated and ambitious Postdoctoral fellow to join the Colorectal Cancer Laboratory led by Dr. Eduard Batlle at the Cancer Science Programme.

The Batlle Lab at IRB Barcelona is an international reference for the study of colorectal cancer (CRC). Their pioneering studies have contributed to advance the state of the art in several important areas such as the connection between stem cells and cancer, the role of the tumor microenvironment in poor prognosis CRC and the identification of mechanisms of metastasis and immune evasion.

The successful candidate will develop an exciting project aiming to understand immune-evasion mechanisms in metastatic CRC. Our laboratory generated the first mouse models for metastatic CRC in a fully immunocompetent context and described a key role for TGF-beta signaling in immune evasion (Tauriello et al. Nature. 2018; Cañellas-Socias et al. Nature. 2022). We are now interested in understanding how immune cells are reprogrammed in the metastatic tumor microenvironment over time. The project will be in close collaboration with the laboratories of Ido Amit (Weizmann Institute) and Holger Heyn (CNAG) and will apply state of the art technologies to track in vivo immune cell dynamics at a single-cell level.


You have

Experience:
- Doctoral degree in Life Sciences (Biology, Biotechnology, Biomedicine, or a related field). Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment.
- Official Accreditation to perform Animal Experimentation

Knowledge and skills:
- Strong background in Tumour Immunology
- Verified skills in cell culture and Molecular Biology
- Good knowledge of Antibody-based tissue analyses, including FACS analyses of tumor cell populations and analysis of imaging data
- Verified skills in In vivo experiments
- Fluent in English.

Competences:
- Self-Motivated
- Good communication skills, both for oral presentations as well as for scientific writing
- High organization capacity
- Ability to interact effectively and work within a team
- Good analytical and problem-solving skills

You might also have

Experience:
- Organoid Culturing
- At least one (first-author) research paper during your PhD
- Proven experience in immunology

Knowledge:
- Candidates with experience with big data analyses, and coding with R and/or Python will be prioritized.

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