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Department : European projects management
Is the Hosting related to staff position within a Research Infrastructure? No
Join the Molecular Microbiology Research Group at the Institute for Health Research of the Principality of Asturias (ISPA), managed by the Foundation for Biosanitary Research and Innovation of Asturias (FINBA), for Marie Skłodowska-Curie Postdoctoral Fellowships (MSCA-PF) 2025.
Description of the institution
FINBA is a leading institution based in Asturias, Spain, dedicated to advancing biomedical research and health innovation. We bring together scientific excellence, clinical expertise, and a strong translational focus aimed at improving health outcomes.
Our mission is to drive cutting-edge biosanitary research, accelerate the translation of scientific discoveries into clinical solutions, and foster innovation that enhances health and well-being at regional, national, and European levels.
It has been created as the management structure of the ISPA, grouped around the Central University Hospital of Asturias (HUCA), and also as a tool for managing R&D&I for all healthcare centers under the Health Service of the Principality of Asturias (SESPA). Currently, it is composed of nearly 1,000 affiliated researchers, organized into key areas of growing importance for global health, including Biotechnology and Biomedical Analyses, Immunology, Microbiology, and Infection, Cancer, Metabolism, Cardiology, Respiratory, and Renal Research, Neurosciences and Sensory Organs, Primary Care, Microbiome Research, Aging Research, and Care Research. Located within the HUCA, the FINBA–ISPA complex provides state-of-the-art facilities for scientific work and fosters collaboration between clinicians, researchers, and industry professionals.
Introduction to the Research Group
The Molecular Microbiology Group (IPLA-CSIC) studies lactic acid bacteria (LAB) and their bacteriophages, aiming to improve food safety, quality, and consumer health. LAB are essential in the Dairy Industry, used as starter cultures in fermented dairy foods like cheese. Their long history of safe consumption and EFSA’s QPS status highlight their safety. Some strains produce beneficial effects, such as improving digestibility, preventing pathogen colonization, or acting as immunological adjuvants. Our work explores their use as starter cultures, probiotics, and vectors for therapeutic molecules.
Project
LAB play a key role in cheese ripening through casein proteolysis, affecting texture and flavor. Some produce neuroactive compounds like GABA, which can help treat stress. GABA-producing LAB are potential probiotics, enabling the creation of functional dairy foods. Other amino acids like phenylalanine, tryptophan, and arginine produce NAC such as phenylethylamine, tryptamine, and agmatine, which have therapeutic potential.
The main goal is to isolate and characterize NAC-producing LAB to develop them as cell factories for natural NAC production, used as starter or adjunct cultures in dairy foods, or as psychobiotics for neuro-gastroenteric and psychiatric disorders.
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