Investigador Posdoctoral

CSIC; Santander; Presencial; EUR 30.000 - 40.000; Jornada completa

Descripción de la vacante

Le CSIC recherche un chercheur postdoctoral pour son équipe en Tumour Microenvironment à IBBTEC. Le candidat travaillera sur des dispositifs microfluidiques pour analyser la perfusion des médicaments dans les tumeurs. Ce poste de 2,5 ans, débutant en été 2025, requiert un doctorat et une expérience en biologie du cancer.

Formación

• Chercheur motivé avec initiative et expériences en biologie cellulaire moléculaire.
• Compétences en conception d'expériences, rédaction de rapports, et supervision.
• Doit avoir la citoyenneté espagnole ou de l'UE.

Responsabilidades

• Concevoir et réaliser des analyses pour valider les résultats.
• Développer des dispositifs microfluidiques et réaliser une caractérisation moléculaire.
• Contribuer aux rapports scientifiques et publications.

Conocimientos

biologie cellulaire moléculaire

techniques de microscopie

conception d'expériences

rédaction de rapports

surveillance

participation d'équipe

Educación

PhD en biologie du cancer, angiogenèse ou domaines connexes

Descripción del empleo

Job Offer: Postdoctoral Researcher in Tumour Microenvironment (TME) Team at Instituto de Biomedicina y Biotecnologia de Cantabria (IBBTEC), CSIC/Universidad de Cantabria

Project Overview

Focus: Modulating cancer-associated fibroblasts (CAFs) to normalize aberrant vascularization in tumors, enhancing drug perfusion and anti-cancer drug efficacy. Funded by ERC CoG.

Research Team

We are a team of 9 researchers, including PI, 4 postdocs, 1 technician, 1 bioinformatician, and 2 PhD students, with strong funding and clinical collaborations.

Research Interests

Investigating the multicellular context of solid tumours, mechanisms of cancer progression, and therapy response, with a focus on CAFs using cellular/animal models, molecular analysis, and bioinformatics.

Project Description

This subproject explores how CAFs influence drug perfusion and therapy, employing microfluidic organ-on-chip devices to study vasculogenesis and related cellular/molecular determinants.

Candidate Responsibilities

• Design and perform analyses to validate findings and guide follow-up studies.
• Work on projects related to CAF heterogeneity, immune interactions, and molecular mechanisms.
• Develop microfluidic devices, conduct advanced microscopy, perform molecular characterization, and contribute to scientific reports and publications.

Candidate Profile

Motivated researcher with initiative, experience in molecular cell biology, microscopy techniques, and leadership skills. Proficiency in experiment design, report writing, supervision, and team participation required.

Requirements

• PhD in cancer biology, angiogenesis, or related fields.
• Experience with wet-lab techniques and microscopy.
• Spanish/EU citizenship.

Application Process

Send a motivation letter, career summary, and CV to Fernando Calvo with the subject "Job Offer May 2025". Reference letters are optional. Shortlisted candidates will be interviewed via videoconference. The position starts Summer 2025, for 2.5 years with possible extension.