Head of Biomarker Strategy & Translational Diagnostics

Tamarind Intelligence; Madrid; Híbrido; EUR 120.000 - 180.000; Jornada completa

Ventajas ofrecidas por este puesto de trabajo

Hybrid working options

Full-time permanent contract

Professional development opportunities

International collaborative atmosphere

Competitive salary

Descripción de la vacante

Amadix is seeking an experienced scientific leader to define and drive our biomarker strategy in oncology, bridging cutting-edge science with real-world diagnostic applications.

The successful candidate will lead the biomarker development journey from discovery and analytical validation to diagnostic assays, regulatory approval and clinical implementation.

Formación

• PhD in Molecular Biology, Oncology, Biotechnology, Biomedical Sciences or related field preferred.
• Strong track record translating biomarker discoveries into diagnostics.
• Experience developing and validating analytical assays for biomarker-based diagnostics.

Responsabilidades

• Define and lead biomarker strategy from discovery to clinical implementation.
• Oversee development, optimization and validation of biomarker assays.
• Lead analytical and clinical studies to support regulatory approval.
• Guide data analysis and interpretation with bioinformatics and biostatistics teams.
• Coordinate cross-functional projects across R&D, Regulatory, Quality and Business.
• Build external partnerships with academia, clinicians and industry.

Conocimientos

Biomarker development

Translational oncology

miRNA biomarkers

protein biomarkers

IVD assay development

analytical validation

clinical implementation

RT-qPCR

qPCR

Digital PCR

ELISA

Immunoassays

Multiplex

Luminex

QuantStudio Real-Time PCR

KingFisher

biomarker data interpretation

statistical analysis

bioinformatics

cross-functional leadership

communication

Educación

PhD in Molecular Biology

Life Sciences degree (Master/Bachelor)

Herramientas

Luminex technology

QuantStudio Real-Time PCR System

KingFisher nucleic acid extraction

Descripción del empleo

Company Description:

Amadix is a molecular diagnostics company specializing in liquid biopsy tests for early cancer detection. The company focuses on developing innovative and disruptive technologies that can identify cancer years before symptoms appear. Amadix is driven by a mission to extend people's lives by enabling earlier and more accurate diagnosis. Team members collaborate in a science-driven, fast-paced environment that bridges cutting-edge research and clinical application. Joining Amadix offers the opportunity to contribute directly to advancing cancer diagnostics and patient outcomes.

Role Description:

We are looking for an experienced scientific leader to define and drive our company's biomarker strategy in oncology, bridging cutting-edge science with real‑world diagnostic applications.

This is a unique opportunity for someone passionate about translating biomarker discoveries into clinically validated diagnostic solutions that improve patient outcomes.

The successful candidate will lead the biomarker development journey---from biomarker discovery and analytical validation to the development of proprietary diagnostic assays, regulatory approval and their implementation in clinical practice.

This role combines strategic leadership with a strong hands‑on approach. You will work across R&D, Clinical Development, Regulatory Affairs, Quality and Business teams, ensuring that scientific discoveries are successfully transformed into robust, clinically meaningful diagnostic products.

Key responsabilities:

• Biomarker Strategy: Define and lead biomarker strategies from identification and validation to clinical implementation.
• Assay & Diagnostic Development: Lead the development, optimization and validation of biomarker-based assays and diagnostic platforms.
• Clinical & Analytical Validation: Oversee analytical and clinical studies supporting regulatory approval and clinical implementation.
• Scientific & Data Leadership: Guide biomarker research, data analysis and interpretation in collaboration with bioinformatics and biostatistics teams.
• Cross-functional Leadership: Lead multidisciplinary projects across R&D, Clinical, Regulatory, Quality and Business teams.
• External Collaboration: Build strategic partnerships with academic, clinical, technology and industry stakeholders.

We are looking for a senior professional with:

• 10 years of experience in biomarker development
• Extensive experience in translational oncology and biomarker discovery, validation and translational diagnostics
• Deep expertise in oncology biomarkers, particularly: miRNA and protein biomarkers
• Proven experience in diagnostic/IVD assay development, analytical validation and clinical implementation
• Experience translating biomarkers into clinically validated diagnostic products
• Strong hands‑on experience and in-depth technical knowledge of routine molecular biology and protein analysis techniques, including RT‑qPCR, qPCR, Digital PCR (preferred), ELISA, Immunoassays, Multiplex.
• Extensive experience with analytical platforms, including: Luminex® technology, QuantStudio™ Real-Time PCR System (or similar) and KingFisher™ Nucleic acid extraction platforms
• Proven expertise in thedevelopment, optimization and validation of analytical assays, reagents and laboratory workflowsfor biomarker-based diagnostic applications.
• Experience interpreting biomarker data andtranslatingscientific evidence into clinically meaningful diagnostic solutions.
• Working knowledge ofstatistical analysis and bioinformatics toolsapplied to biomarker
• Strong analytical and strategic skills, with the ability to interpret complex data and support biomarker strategy, portfolio prioritization and resource allocation
• Proven experience leading cross‑functional scientific programs across clinical, regulatory, commercial and technical teams
• Strong leadership and communication skills, including team management, mentoring and the ability to communicate complex scientific concepts to diverse stakeholders
• Experience collaborating with external partners, including academic institutions, clinical investigators and industry stakeholders

Preferred experience:

• Experience with liquid biopsy, proteomics, NGS‑based biomarker discovery or Companion Diagnostics (CDx)
• Knowledge of ISO 13485, IVDR and Design Control principles

Background education:

• PhDin Molecular Biology, Oncology, Biotechnology, Biomedical Sciences or a related scientific discipline is strongly preferred.
• Master's or Bachelor's degree in Life Sciences with extensive relevant experience will also be considered.

This is an opportunity to work at the intersection of biomarker science, diagnostics and precision oncology, helping translate scientific innovation into solutions with the potential to improve patient care.

What We Offer:

• A competitive salary commensurate with experience.
• A full-time, permanent contract.
• Flexible working arrangements, including hybrid working options.
• Continuous learning and professional development opportunities.
• A collaborative, international, and innovative working environment.
• The opportunity to contribute to groundbreaking advancements in precision oncology and biotechnology.

Location

Madrid

Contact

[e-mail]