Exploring the Interplay of Immunogenic small RNAs and RNA Sensors in Neuroinflammation : Insigh[...]

Universitat de Barcelona; Santiago de Compostela; Presencial; EUR 30.000 - 45.000; Jornada completa

Descripción de la vacante

L'Université de Barcelone recrute un postdoctorant en chimie médicinale pour un contrat temporaire de 16 mois. Le candidat sera impliqué dans la synthèse, isolation et caractérisation de composés chimiques, ainsi que dans la supervision et la gestion des activités de laboratoire. Ce poste nécessite un docteur en chimie médicinale avec une expérience significative en chimie synthétique.

Formación

• Plus de 2 ans d'expérience postdoctorale dans une autre université.
• Expérience dans l'optimisation hit-to-lead.
• Extraire, purifer et caractériser des composés hautement polaires.

Responsabilidades

• Synthèse chimique et caractérisation de composés fluorescents.
• Superviser des membres moins expérimentés de l'équipe.
• Préparer des rapports et des présentations pour des réunions.

Conocimientos

Chimie médicinale

Supervision

Développement de méthodologies synthétiques

Caractérisation de composés fluorescents

Gestion de stocks

Engagement dans des activités de sensibilisation

Educación

PhD en chimie médicinale

Diplôme en pharmacie ou chimie

Master en chimie médicinale ou chimie organique

Herramientas

ChemOffice

MestreNova

SciFinder

Reaxys

Descripción del empleo

Organisation / Company Universitat de Barcelona Department Organisation profile Research Field Chemistry Researcher Profile Recognised Researcher (R2) Positions Postdoc Positions Country Spain Application Deadline 15 May 2025 - 23 : 59 (Europe / Madrid) Type of Contract Temporary Job Status Full-time Hours Per Week 37,5 Offer Starting Date 2 May 2025 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

Chemical synthesis, isolation, purification and chemical characterization of analogues of an antimalarial lead compound and different chemical probes and fluorescent derivatives thereof to be used in pull-down studies. Supervision of less-experienced members of the team working in the project. Preparation of reports and presentations for regular meetings. Organization of outreach activities. Management of stocks of reagents, solvents, and chromatographic material.

Degree in Pharmacy or Chemistry (+ Master in Medicinal Chemistry or Organic Chemistry), PhD in Medicinal Chemistry, experience in medicinal chemistry projects, with hit-to-lead optimization

Specific Requirements

Over 2 years of postdoctoral experience in a different university to that of the PhD degree; experience in the development of synthetic methodologies; experience in the synthesis and characterization of fluorescent compounds; experience in the isolation, purification and characterization of highly polar polyfunctionalized compounds; highly qualified in structural elucidation by spectroscopic techniques; experience in supervision of pregraduate students; experience in the management of stocks of reagents, solvents, and other consumables for a med chem laboratory; training or experience in intellectual property, transfer activities, valorisation projects and / or biotech companies; highly qualified user of ChemOffice, MestreNova, SciFinder, and Reaxys; engagement in outreach activities.

Additional Information

Eligibility criteria

• Suitability of the CV for the required tasks (50)
• Relevant experience with regard to the required tasks (30)

Selection process

Selection based on the eligibility criteria, performed by the following committee :

• Núria Llor Brunés (Director of the Department of Pharmacology, Toxicology and Therapeutic Chemistry, University of Barcelona)
• Diego Muñoz-Torrero López-Ibarra (PI of the project, from partner University of Barcelona)
• Xavier Fernàndez Busquets (coordinator of the project, from IBEC and ISGlobal)

Additional comments

Duration of the contract of employment : 16 months

Work Location(s)

Number of offers available 1 Company / Institute Laboratory of Medicinal Chemistry - Department of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Food Sciences Country Spain State / Province Barcelona City Barcelona Postal Code 08028 Street Avda. Joan XXIII, 27-31 Geofield

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