2026/141: 1 T4A Junior Higher Technician

Institut d'Investigació Biomèdica Sant Pau; España; On-site; EUR 30,000 - 42,000; Full time

Job summary

Institut d'Investigació Biomèdica Sant Pau invites applications for a T4A Junior Higher Technician in the Cellular Immunotherapy and Gene Therapy Group. The role focuses on manufacturing CART cells under GMP standards and supporting GMP processes in a multicenter research setting.

The position requires a Higher Education degree, knowledge of two Catalan official languages or a plan to acquire them within a year, and an intermediate level of English.

Qualifications

• Higher Education degree (Bachelor's Degree, University Diploma, or equivalent).
• Two official languages of Catalonia or commitment to acquire proficiency within one year.
• Intermediate level of English.
• Intermediate level of office software tools (Excel, Word, PowerPoint).

Responsibilities

• Manufacture CART cells in GMP-compliant facilities.
• Prepare lentiviral vectors under GMP regulations in clean room.
• Inventory control and materials mgmt per GMP standards.
• Draft GMP manufacturing protocols and records for vectors and CART cells.
• Support quality control activities including flow cytometry and qPCR.
• Prepare incident and non-conformity reports.
• Assist with equipment maintenance and calibration.

Skills

English (intermediate)

Office tools

Education

Bachelor's degree or equivalent

Job description

Organisation/Company Institut d'Investigació Biomèdica Sant Pau Research Field Other Researcher Profile Other Profession Positions Bachelor Positions Application Deadline 30 Oct 2026 - 15:00 (Europe/Madrid) Country Spain Type of Contract Permanent Job Status Full-time Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

Call for applications for a T4A Junior Higher Technician position within the Department of Hematologic Oncology and Transplantation (Cellular Immunotherapy and Gene Therapy Group). Application deadline: 30 October 2026 at 3:00 p.m.

About the Unit / Research Group

The Cellular Immunotherapy and Gene Therapy Group (GITG) within the Hematology Department focuses on the study of genetically modified T cells expressing chimeric antigen receptors (CARs) and their clinical application in patients with hematological malignancies.

The GITG at IR Sant Pau is a well-established research group that develops and manufactures advanced CART therapy products for the treatment of patients with lymphoid hematological malignancies.

Our group initiated a first-in-Europe Phase I clinical trial using CART30 cells (HSP-CAR30) for patients with Hodgkin lymphoma, and the Phase II study is currently ongoing. During 2024, a second clinical trial was launched in patients with refractory B-cell lymphomas using selected memory T cells expressing CAR19 (HSP-CAR19M). Both HSP-CAR30 and HSP-CAR19M products are fully manufactured at Sant Pau by the GITG according to Good Manufacturing Practice (GMP) standards.

Current research lines focus on:

• Investigating the antitumor efficacy of memory T-cell subsets.
• Studying the antitumor efficacy of genetically modified stem memory T cells expressing CARs.
• Developing innovative fourth-generation CARs targeting antigens expressed in hematological malignancies.
• Developing academic CART immunotherapy clinical trials for patients with lymphoid malignancies.
• Minimum qualification required: Higher Education degree (Bachelor's Degree, University Diploma, or equivalent).
• Oral and written proficiency in the two official languages of Catalonia or, alternatively, the selected candidate must demonstrate, or commit to acquiring within a maximum period of one year, an adequate command of both official languages.
• Intermediate level of English.
• Intermediate level of office software tools (Excel, Word, PowerPoint, etc.).

The following will be valued

• Knowledge of immunology, immunotherapy, tumour immunology assays, and molecular biology techniques (qPCR).
• Experience in the development of CART therapies.
• Experience in flow cytometry and cell culture techniques.

Duties

• Manufacturing advanced therapy medicinal products (CART cells) in compliance with GMP standards.
• Manufacturing lentiviral vectors under GMP regulations within the Advanced Therapies Unit of IR Sant Pau (Clean Room Facility).
• Inventory control and materials management in accordance with GMP requirements.
• Drafting and preparing protocols and records associated with GMP manufacturing of lentiviral vectors and CART cells.
• Supporting quality control activities for GMP CART-cell manufacturing, including flow cytometry, cytotoxicity assays, and qPCR analyses.
• Preparing reports on incidents and non-conformities related to the assigned work environment.
• Supporting equipment control, maintenance, and calibration activities.
• Performing equipment maintenance and review tasks.

We Offer

• Permanent contract linked to the research line: “CART Therapy for Hematological Cancer.”
• Annual workload of 1,627.5 hours (37.5 hours per week).
• Salary according to the applicable collective agreement.
• Integration into the Hematologic Oncology and Transplantation Group.

The deadline for submitting applications is 30 October 2026 at 3:00 p.m.