2025_69_OPEN CALL FOR MSCA - POSTDOCTORAL FELLOWSHIP

European Commission; España; Presencial; EUR 5.000 - 60.000; Jornada completa

Descripción de la vacante

A prestigious research institution in Spain is seeking a Postdoctoral Researcher to join their Neuromuscular Research Group. The successful candidate will focus on groundbreaking research involving long-read sequencing technologies related to myotonic dystrophy type 1. This role offers an excellent opportunity to work in an interdisciplinary environment and develop innovative methodologies to uncover novel disease mechanisms.

Servicios

Living allowance: 5990€ per month

Mobility allowance: 710€ per month

Family allowance (if applicable): 660€

Training capsules by the company

23 days holiday plus additional leave days

Formación

• Must have a maximum of 8 years full-time equivalent experience in research.
• Fluent in English (both written and spoken).
• Demonstrated experience in two or more relevant areas.

Responsabilidades

• Design and execute experiments involving long-read sequencing.
• Integrate multi-omics data to investigate disease mechanisms.
• Prepare scientific publications and engage with MSCA network.

Conocimientos

Bioinformatics

Molecular Genetics

Genomics

Neurobiology

Educación

Doctoral degree

Herramientas

Long-read sequencing technologies

Linux/Unix environment

Descripción del empleo

FUNDACIO INSTITUT D'INVESTIGACIO EN CIENCIES DE LA SALUT GERMANS TRIAS I PUJOL

Organisation/Company FUNDACIO INSTITUT D'INVESTIGACIO EN CIENCIES DE LA SALUT GERMANS TRIAS I PUJOL Research Field Medical sciences » Health sciences Researcher Profile Recognised Researcher (R2) Positions Postdoc Positions Country Spain Application Deadline 15 Jun 2025 - 23:59 (Europe/Madrid) Type of Contract Temporary Job Status Full-time Hours Per Week 39 Is the job funded through the EU Research Framework Programme? Horizon Europe - MSCA Reference Number HORIZON-MSCA-2025-PF-01-01 Is the Job related to staff position within a Research Infrastructure? No

Offer Description

The selected candidate will join the Badalona Neuromuscular Research Group (GRENBA), an interdisciplinary team based at the IGTP. The group integrates clinical, experimental, and computational approaches to investigate rare neuromuscular diseases, with a particular focus on myotonic dystrophy type 1 (DM1). The fellow will contribute to the research line focused on the application of long-read sequencing technologies to study the repetitive region associated with DM1. Additionally, the candidate will develop and implement innovative transcriptomic and metabolomic methodologies aimed at uncovering novel disease mechanisms.

MAIN RESPONSIBILITIES

The research project will focus on the comprehensive characterization of the pathogenic DMPK repeat expansion associated with myotonic dystrophy type 1 (DM1), using cutting-edge long-read sequencing technologies. The specific tasks and responsibilities include:

• Design and execution of experiments involving long-read sequencing to analyse repeat length, sequence interruptions, somatic mosaicism, and methylation patterns at the DMPK locus.
• Bioinformatic processing and analysis of long-read data, including the development or adaptation of pipelines to study repetitive and epigenetically regulated regions.
• Integration of multi-omics data, including transcriptomic and metabolomic datasets, to investigate disease mechanisms and identify potential biomarkers.
• Collaboration with clinical and experimental teams to ensure translational relevance of the findings and contributions.
• Preparation of scientific publications, conference presentations, and reports derived from the project outcomes.
• Engagement with the broader MSCA network, including participation in training activities and workshops.

Candidate must comply with the MSCA Postdoctoral Fellowships 2025 (HORIZON-MSCA-2025-PF-01) eligibility criteriaset by the call:

• Supported fellows:Must be in possession of doctoral degree. At the call deadline (10-09-2025), supported researchers must have a maximum of 8 years full time equivalent experience in research, measured from the date that the researcher was in a possession of a doctoral degree and certified by appropriate documents.
• Nationality: Any.
• Mobility: The researcher must not have resided or carried out his/her main activity (work, studies, etc.) in the country of the host organization for more than 12 months in the 3 years immediately prior to the deadline.
• Researchers wishing to reintegrate from a third country must either be based in a third country at the call deadline, or have moved directly from a third country to an EU Member State or Horizon Europe Associated Country within the last 12 months before the call deadline.
• Must be fluent in English (both written and spoken)
• Candidates with an oustanding record of Research achievements and publications

Specific Requirements

We are looking for talented and innovative scientist with a strong background in molecular genetics, genomics, bioinformatics, and/or neurobiology. We seek highly motivated researchers capable of working both independently and as part of a multidisciplinary team.

• Ideal candidates will have demonstrated experience in two or more of the following areas
• Long-read sequencing technologies.
• Analysis of repetitive DNA regions, structural variants, or somatic mosaicism.
• Transcriptomic or epigenomic profiling.
• Bioinformatics and data analysis in a Linux/Unix environment.
• Rare disease research, especially in neuromuscular or neurogenetic disorders.

Languages ENGLISH Level Excellent

Research Field Medical sciences » Health sciences Years of Research Experience 4 - 10

Additional Information

Contribution for the recruited researcher per person monthly:

• Living allowance: 5990€
• Mobility allowance: 710€
• Family allowance (if applicable): 660€ x % covered by the beneficiary
• Long-term leave allowance (if applicable): 6700€
• The candidate can be only incorporated with an obtention of a MSCA-PF-2024 or similar.
• 23 days holiday and 5 days for personal matters +2 days for Easter + 2 days for Christmas .
• Training capsules by the company.
• Be part of an excellent multidisciplinary research centre with the HRS4R badge.
• Location on the Can Ruti Campus, a first-class translational research environment in the Barcelona area, in a very stimulating scientific environment. The IGTP offers a supportive, friendly and collaborative ecosystem to promote professional development and help you achieve your research goals.

Selection process

Interested persons must attach to the application:

• Motivation letter explaining their interest in the position.
• Short CV (max 2 pages)
• Contact of 2-3 references.

Applications will be evaluated in accordance with the guiding principles and objectives of the supply systems, following the process described below:

• Curricular evaluation: analysis of the curriculum vitae to assess aspects related to training, professional career and experience in positions related to the job position under selection.
• Personal interview: once the résumé has been evaluated, the selected candidates will be called for a personal interview to verify and expand on the information detailed in the résumé and to evaluate aspects related to experience and professional skills.

Applications that do not meet the requirements, that are not included in the cases foreseen or that are not processed in accordance with the established procedure will not be considered in the selection process.

Additional comments

• Deadline of the next call for proposals for MSCA - Postdoctoral Fellowships is September, 10th 2025.
• You can send this Expression of interest to the contact person before 15/06/2025
• Proposals will be pre-selected on the basis of internal evaluation. Candidates will be informed of the results.

Work Location(s)

Number of offers available 1 Company/Institute FUNDACIÓ INSTITUT D'INVESTIGACIÓ EN CIÈNCIES DE LA SALUT GERMANS TRIAS I PUJOL Country Spain State/Province BARCELONA City BADALONA Postal Code 08916 Street CTRA DE CAN RUTI/ CAMI DE LES ESCOLES S/N

CTRA DE CAN RUTI/ CAMI DE LES ESCOLES S/N