2025-002-01 _ Postdoc : Metabolism of Aging and Tumorigenesis

The Vall d´Hebron Institute of Oncology (VHIO) seeks a Postdoc position : Metabolism of Aging and Tumorigenesis – investigate how the metabolically aged tissue microenvironment promotes immune evasion and cancer

Reference : 2025-002-01

Number of vacancies : 1

Are you passionate about aging research and cancer biology ? Do you want to lead the way in understanding how metabolic bottlenecks created by aging promote tumorigenesis and undermine tumor surveillance?

The Aging and Cancer Lab at the Vall d´Hebron Institute of Oncology (VHIO) in Barcelona , Spain, headed by Dr. Mate Maus, is inviting applications from ambitious postdoc candidates to join our pioneering team. We are investigating how aging-associated metabolic bottlenecks shape the precancerous tissue microenvironment, promote tumorigenesis , and compromise anti-tumor immunity . Join us in advancing the next generation of preventive and therapeutic strategies to combat cancer.

About the Project

Our lab is uncovering how aging processes and cancer therapies contribute to metabolic dysfunction in cells and tissues, leading to the selection of precancerous cells and the failure of adaptive immune responses .

• Study in a translational research environment how aging and cancer therapy create metabolic bottlenecks and thereby promote the selection of precancerous cells and the failure of adaptive immune cells.
• Leverage cutting-edge technologies in metabolism, cancer biology, immunology, and aging research.
• Use organoids, cell cultures, mouse models , and human tissues to bridge preclinical and clinical oncology.

Why This Opportunity?

• Contribute to high-impact research with direct implications for cancer prevention and immunotherapy .
• Join a dynamic international team at the crossroads of tumor immunology, oncology, and aging research.
• Push the boundaries of translational oncology.
• Live and work in Barcelona , a vibrant and diverse city with a thriving scientific community.

What We Offer

• A supportive and diverse environment , where English is the working language.
• Mentorship and career development opportunities.
• Access to state-of-the-art facilities and the opportunity to work on a project with high visibility.
• A full-time postdoctoral contract with a competitive salary based on experience.

The ideal candidate :

• Extensive experience with in vivo mouse models (essential).
• A PhD in immunology, metabolism, cancer research, or aging research .
• A strong publication record , with at least one first-author paper published or deposited as a preprint.
• Experience with single-cell transcriptomics , and / or CRISPR / Cas9 genome editing (advantageous).
• Excellent communication skills in English.
• A creative mindset and a team-oriented approach.
• Curiosity, independence , and dedication to improving outcomes for cancer patients .

Vall d’Hebron Institute Oncology (VHIO) endorses the Requirements and Principles of the European Charter for Researchers, the Code of Conduct for the Recruitment of Researchers promoted by the European Commission and follows Equal Opportunities policies.

On 10th April 2018, VHIO was awarded the “HR Excellence in Research” logo. Our Institute was consequently granted permission to use the HR Excellence in Research Award logo as a demonstration of its stimulating and favorable work environment in line with the Charter & Code.