Senior Pharmacometrician: Model-Informed Drug Development

Ascendis Pharma; Gentofte Kommune; Sur place; DKK 900 000 - 1 300 000; Plein temps

Avantages offerts par ce poste

Travel 5–10 days/year

Résumé du poste

Ascendis Pharma seeks a Specialist/Senior Specialist Pharmacometrician to lead hands-on pharmacometric analyses across translational and clinical programs. You will apply model-informed drug development to support trial design, dose selection, and evidence generation in rare diseases, contributing to regulatory submissions and portfolio decisions.

You will work with cross-functional teams, maintain high-quality standards, and influence development strategies globally.

Qualifications

• Hands-on experience with PK/PD modeling and model-informed drug development.
• Experience with translational and clinical-stage analyses, including population PK/PD, exposure–response, and dose selection.

Responsabilités

• Develop model-informed drug development strategies for translational and clinical-stage projects.
• Shape regulatory strategy and represent pharmacometrics in global health authority interactions.
• Inform dose selection and trial design through population PK/PD modeling and simulations.
• Translate quantitative results into clear recommendations for project teams and authorities.
• Document and report analyses to submission standards.

Connaissances

NONMEM

R

PK/PD modeling

Regulatory submissions

Formation

PhD/MSc in pharmacometrics

Outils

LaTeX

Git

Description du poste

Ascendis Pharma seeks a Specialist/Senior Specialist Pharmacometrician to lead hands-on pharmacometric analyses across translational and clinical programs. You will apply model-informed drug development to support trial design, dose selection, and evidence generation in rare diseases, contributing to regulatory submissions and portfolio decisions.

You will work with cross-functional teams, maintain high-quality standards, and influence development strategies globally.